Evidence map›Paper›PMID 41286485›Full record

ReviewNature plants2025

Advances and prospects of large DNA fragment editing in plants.

Yidi Zhao, Yingbo Liang, Zhongfu Ni, Qixin Sun, Yuan Zong, Yanpeng Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature plants, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Structural Variation and Its Roles in Plant Genomes.Plants (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yidi Zhao *Frontiers Science Center for Molecular Design Breeding (MOE), State Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, China Agricultural University, Beijing, China.ORCID 0009-0000-1095-5511
Yingbo Liang *Laboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0002-3246-733X
Zhongfu NiFrontiers Science Center for Molecular Design Breeding (MOE), State Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, China Agricultural University, Beijing, China.ORCID 0000-0003-4524-7720
Qixin SunFrontiers Science Center for Molecular Design Breeding (MOE), State Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, China Agricultural University, Beijing, China.ORCID 0000-0002-3819-6892
Yuan ZongFrontiers Science Center for Molecular Design Breeding (MOE), State Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, China Agricultural University, Beijing, China. zongyuan@cau.edu.cn.ORCID 0000-0003-0576-6614
Yanpeng WangLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. yanpengwang@genetics.ac.cn.ORCID 0000-0003-1577-6883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structural variations drive plant genome evolution and shape agronomic traits. Manipulating structural variations has great potential to improve complex plant traits and enhance agricultural sustainability. Genome editing technologies have evolved from gene knockouts and base editing to the modification of short DNA fragments, and are now advancing towards the precise manipulation of large DNA fragments. This advancement facilitates targeted, large-scale genomic changes such as deletions, insertions, replacements, inversions, translocations and duplications. In this Review, we summarize recent advances in developing technologies for large DNA fragment editing and highlight their key applications in plants as well as their potential to accelerate crop improvement. Finally, we discuss the current challenges and future prospects for these technologies in plant science.

Indexed as

Crops, AgriculturalDNA, PlantGene EditingGenome, PlantPlantsCRISPR-Cas SystemsPlants, Genetically ModifiedDNA, Plant

Identifiers

PMID41286485

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.