Evidence map›Paper›PMID 41286483›Full record

ReviewWorld journal of pediatrics : WJP2026

Position statement of the Mexican Association of Pediatrics on the immunoprevention of respiratory syncytial virus infection during pregnancy and infancy.

Claudia Montesinos Ramírez, Patricia Saltigeral Simental, Federico Javier Ortiz Ibarra, Martha Josefina Avilés Robles, César Adrián Martínez Longoria, Rodolfo Norberto Jiménez-Juárez, José Alberto Castillo, Zigor Campos Goenaga, Carlos López Candiani, Alfonso Copto García and 13 more

Abstract readReview
In one paragraph

Review in World journal of pediatrics : WJP, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Claudia Montesinos RamírezMexican Association of Pediatrics, Mexico City, Mexico.
Patricia Saltigeral SimentalDepartment of Infectious Disease, National Pediatrics Institute, Mexico City, Mexico.
Federico Javier Ortiz IbarraHospital Ángeles del Pedregal, Camino Sta. Teresa 1055-S, Heroes de Padierna, La Magdalena Contreras, 10700, Mexico City, Mexico. dr_javierortiz@yahoo.com.ORCID 0009-0006-2534-3108
Martha Josefina Avilés RoblesService of Infectious Diseases, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
César Adrián Martínez LongoriaSchool of Medicine and Health Sciences, Tecnologico de Monterrey, Monterrey, Mexico.
Rodolfo Norberto Jiménez-JuárezDepartment of Infectious Diseases, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
José Alberto CastilloMexican Association of Pediatrics, Mexico City, Mexico.
Zigor Campos GoenagaHigh Specialty Medical Unit, IMSS Gynecology and Obstetrics Hospital No. 4 "Luis Castelazo Ayala", Mexico City, Mexico.
Carlos López CandianiMexican Association of Pediatrics, Mexico City, Mexico.
Alfonso Copto GarcíaMedical Society of Hospital Ángeles México, Mexico City, Mexico.
Elsa Diaz LópezMexican College of Obstetrics and Gynecology Specialists, Mexico City, Mexico.
Vianey Escobar RojasISSSTE Pediatric Society, Mexico City, Mexico.
María Del Carmen Gorbea RoblesInfectious Disease Hospital, IMSS Centro Médico La Raza, Mexico City, Mexico.
Georgina Hernando BecerraSociety of Pediatricians and Neonatologists, "Professor Dr. José Iglesias Leboreiro", Mexico City, Mexico.
Patricia Laurean IbarraMexican Society of Pediatrics, Mexico City, Mexico.
Antonio Luévanos VelázquezMexican Academy of Pediatrics, Mexico City, Mexico.
Brandon Ortiz-CasasDepartment of Science, Tecnológico de Monterrey, Campus Ciudad de México, Mexico City, Mexico.
Francisco Javier Otero MendozaDepartment of Infectious Disease, National Pediatrics Institute, Mexico City, Mexico.
Mitchel Martín Padilla RojasMexican Association of Pediatrics, Mexico City, Mexico.
José Luis Pinacho VelázquezGuadalajara Civil Hospital, Guadalajara, Mexico.
Lucila Del Carmen Sánchez OrtizMexican Association of Pediatrics, Mexico City, Mexico.
Silvia F Torres LiraMexican Society of Pediatrics, Mexico City, Mexico.
Víctor Saúl Vital ReyesMexican College of Obstetrics and Gynecology Specialists, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus infection is one of the leading causes of morbidity and mortality in children under two years of age. Thus, the objective of this consensus document is to analyze and discuss current scientific evidence and generate recommendations that reflect the position of a prominent national pediatric professional association regarding the benefits and impact of immunoprophylaxis in pregnant women and infants on the burden of respiratory syncytial virus-related respiratory disease in Mexico and Latin America. DATA SOURCES: Following an academic consensus model, the available scientific literature on current or controversial topics was compiled and critically analyzed. The process adhered to the Guidelines for the Development of Consensus Documents and incorporated recommendations and critical appraisal criteria from the European Appraisal of Guidelines for Research and Evaluation initiative. Multidisciplinary and representative teams were formed from several national professional associations. The studies and manuscripts included in this review were selected via keywords such as respiratory syncytial virus, vaccine, monoclonal antibodies, maternal vaccine, safety and efficacy in vaccine, and vaccine compliance across databases, with priority given to articles published between January 2019 and May 2025. The process included one in-person meeting and one virtual meeting.

resultsA total of nine questions, which were considered unresolved in previous respiratory syncytial virus-related consensus documents, were formulated, covering the time, dose, cost-effectiveness and other perspectives. Each one was addressed through an updated literature review and critical appraisal. The findings and resulting recommendations were presented along with their corresponding level of evidence according to Grading of Recommendations Assessment, Development, and Evaluation.

conclusionsBoth maternal respiratory syncytial virus vaccination (RSVpreF) and passive immunization with nirsevimab demonstrate robust efficacy and favorable safety, protecting newborns and infants from severe respiratory syncytial virus infections. The document provides actionable, evidence-based recommendations tailored for the Latin American healthcare context, aiming to reduce severe respiratory syncytial virus disease incidence and improve national infant health outcomes.

Indexed as

Pregnancy Complications, InfectiousRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus VaccinesFemaleHumansInfantInfant, NewbornMexicoPediatricsPregnancySocieties, MedicalRespiratory Syncytial Virus VaccinesImmunoprophylaxisMonoclonal antibodiesPosition statementRespiratory syncytial virusVaccination and pregnancy

Identifiers

PMID41286483
PMCPMC12894137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.