Evidence map›Paper›PMID 41286373›Full record

ReviewEuropean journal of pediatrics2025

Beyond the seizure: the role of post-event observation in febrile seizure management.

Gidon Test, Ana Luiza Zigman, Doron Pasternak, Dennis Scolnik, Vered Wiesel, Yousef Abu El Hasan, Remah Yousef, Oren Tavor, Inbal Kestenbom, Or Kaplan

Abstract readReview
In one paragraph

Review in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gidon Test *Pediatric Emergency Department, Soroka University Medical Center, Beer-Sheva, Israel. gidontest@gmail.com.ORCID http://orcid.org/0009-0000-0315-912X
Ana Luiza Zigman *Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Doron PasternakFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Dennis ScolnikDivision of Pediatric Emergency Medicine, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada, ON.
Vered WieselFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Yousef Abu El HasanPediatric Department D, Soroka University Medical Center, Beer Sheva, Israel.
Remah YousefPediatric Department D, Soroka University Medical Center, Beer Sheva, Israel.
Oren TavorPediatric Emergency Department, Soroka University Medical Center, Beer-Sheva, Israel.
Inbal KestenbomPediatric Emergency Department, Soroka University Medical Center, Beer-Sheva, Israel.
Or KaplanPediatric Emergency Department, Soroka University Medical Center, Beer-Sheva, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simple febrile seizures (SFS) are a common cause of pediatric emergency department (PED) visits. Guidelines discourage extensive workup for children presenting with SFS, but there is little consensus on whether, or how long, to observe these patients. The objective of this study is to identify clinical, demographic, and historical factors associated with short-term seizure recurrence which might merit an observational period in children who have suffered a febrile seizure. This retrospective cohort study included children aged 12 months to 5 years who presented to the PED with a single generalized seizure in the setting of fever ≥ 38 °C. Current hospital policy recommends a 6-h period of observation in the PED for all such children, and admission for those who undergo a second seizure. Statistical analyses included comparisons between children with and without seizure recurrence, and logistic regression to identify predictors of hospitalization. Of 1496 children screened, 1404 met inclusion criteria. Seizure recurrence occurred in 27 (1.9%) of patients-all within 3 h of presentation. None of the following factors predicted seizure recurrence: gender, ethnic group, family history of febrile seizures, prior SFS, duration of fever before seizure, or peak fever.

conclusionThe short-term recurrence of febrile seizures was low (1.9%) and occurred within hours of the index seizure. Since the recurrence rate was low, and considering the benign outcomes of SFS, an observation period may not be warranted. Children who are stable and have regained neurological function may be considered for early discharge with appropriate caregiver education and follow-up, as already practiced in some centers. WHAT IS KNOWN: • Simple febrile seizures are frequent and often benign occurrences in children. • Guidelines discourage extensive tests but omit specific observation protocols. WHAT IS NEW: • Seizure recurrence after simple febrile seizures is very low and usually occurs within the first 3 h after the initial seizure. • After a simple febrile seizure, children may be considered for early discharge once they return to baseline function, without the need for an extended observation period.

Indexed as

Seizures, FebrileChild, PreschoolEmergency Service, HospitalFemaleHospitalizationHumansInfantMaleRecurrenceRetrospective StudiesTime FactorsConvulsionFebrileObservationRecurrence

Identifiers

PMID41286373
PMCPMC12644193

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.