ReviewEuropean journal of pediatrics2025
Beyond the seizure: the role of post-event observation in febrile seizure management.
Review in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Immunological mechanisms and prevention strategies for febrile seizures in children.Frontiers in immunology · 2026Review
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Simple febrile seizures (SFS) are a common cause of pediatric emergency department (PED) visits. Guidelines discourage extensive workup for children presenting with SFS, but there is little consensus on whether, or how long, to observe these patients. The objective of this study is to identify clinical, demographic, and historical factors associated with short-term seizure recurrence which might merit an observational period in children who have suffered a febrile seizure. This retrospective cohort study included children aged 12 months to 5 years who presented to the PED with a single generalized seizure in the setting of fever ≥ 38 °C. Current hospital policy recommends a 6-h period of observation in the PED for all such children, and admission for those who undergo a second seizure. Statistical analyses included comparisons between children with and without seizure recurrence, and logistic regression to identify predictors of hospitalization. Of 1496 children screened, 1404 met inclusion criteria. Seizure recurrence occurred in 27 (1.9%) of patients-all within 3 h of presentation. None of the following factors predicted seizure recurrence: gender, ethnic group, family history of febrile seizures, prior SFS, duration of fever before seizure, or peak fever.
conclusionThe short-term recurrence of febrile seizures was low (1.9%) and occurred within hours of the index seizure. Since the recurrence rate was low, and considering the benign outcomes of SFS, an observation period may not be warranted. Children who are stable and have regained neurological function may be considered for early discharge with appropriate caregiver education and follow-up, as already practiced in some centers. WHAT IS KNOWN: • Simple febrile seizures are frequent and often benign occurrences in children. • Guidelines discourage extensive tests but omit specific observation protocols. WHAT IS NEW: • Seizure recurrence after simple febrile seizures is very low and usually occurs within the first 3 h after the initial seizure. • After a simple febrile seizure, children may be considered for early discharge once they return to baseline function, without the need for an extended observation period.
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