ArticleScientific reports2025
Smartphone-assisted HPTLC for simultaneous determination of vonoprazan fumarate and aspirin: a comparative study with HPTLC densitometry.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Role of Artificial Intelligence in Modern Analytical Chemistry: Current Trends and Future Directions.International journal of analytical chemistry · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smartphone-assisted HPTLC/Image J and HPTLC densitometric methods were developed and validated for the simultaneous determination of vonoprazan fumarate VON and aspirin ASP. Chromatographic separation was carried out using a mobile phase composed of methylene chloride, methanol, and glacial acetic acid in a 60:40:2.0 v/v ratio, yielding well-resolved and symmetric peaks with retention factor Rf values of 0.45 for VON and 0.75 for ASP. Densitometric analysis of chromatograms was performed at 270 nm, showing linearity in the range of 2.0-10 µg/band for VON and 5.0-25 µg/band for ASP. For the smartphone-assisted approach, captured plate images were processed using Image J software to quantify band intensities, providing linearity over 1.0-10 µg/band for VON and 5.0-35 µg/band for ASP. Both methods were validated according to ICH guidelines and successfully applied to pharmaceutical dosage forms, demonstrating good accuracy and precision. Statistical comparison with a reported HPLC method confirmed the reliability of the proposed approaches. Notably, the smartphone-assisted HPTLC/Image J method offers a cost-effective, accessible, and sustainable alternative to conventional HPTLC densitometry, while maintaining comparable accuracy and precision, making it a promising tool for routine pharmaceutical analysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.