Evidence map›Paper›PMID 41286258›Full record

ArticleJournal of general internal medicine2026

COVID-19 Vaccination and Kidney Disease : SARS-CoV-2 Vaccine Effect on Risk of Infection and Subsequent Outcomes in Patients with Chronic Kidney Disease.

Nicholas Carlson, Felix Michalik, Thomas Gerds, Ellen Freese Ballegaard, Morten Buus Jørgensen, Karl Emil Nelveg-Kristensen, Pascal Geldsetzer, Mads Hornum, Bo Feldt-Rasmussen, Christian Torp-Pedersen

Abstract read
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Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicholas CarlsonDepartment of Nephrology and Endocrinology, Rigshospitalet, Copenhagen, Denmark. Nicholas.carlson.01@regionh.dk.ORCID 0000-0002-4374-470X
Felix MichalikDivision of Primary Care and Population Health, Stanford University, Stanford, USA.
Thomas GerdsDepartment of Biostatistics, Copenhagen University, Copenhagen, Denmark.
Ellen Freese BallegaardDepartment of Nephrology and Endocrinology, Rigshospitalet, Copenhagen, Denmark.
Morten Buus JørgensenDepartment of Nephrology and Endocrinology, Rigshospitalet, Copenhagen, Denmark.
Karl Emil Nelveg-KristensenDepartment of Nephrology and Endocrinology, Rigshospitalet, Copenhagen, Denmark.
Pascal GeldsetzerDivision of Primary Care and Population Health, Stanford University, Stanford, USA.
Mads HornumDepartment of Nephrology and Endocrinology, Rigshospitalet, Copenhagen, Denmark.
Bo Feldt-RasmussenDepartment of Nephrology and Endocrinology, Rigshospitalet, Copenhagen, Denmark.
Christian Torp-PedersenDepartment of Cardiology, North Zealand University Hospital, Hilleroed, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenefit of SARS-CoV-2 vaccinations to reduce the risk of infection and subsequent outcomes in patients with impaired kidney function beyond end-stage kidney disease (ESKD) remains uncertain.

objectivesTo evaluate the vaccination effect on rates of SARS-CoV-2 infection and subsequent risk of 30-day mortality outcomes in patients with kidney disease.

methodsPopulation-based retrospective cohort on nationwide data from multiple national health care registers between February 2021 and June 2022. All vaccine uptake and efficacy were evaluated in granular eGFR categories with comparison of age- and gender-standardized rates of SARS-CoV-2 infection and subsequent risks of 30-day mortality between unvaccinated, vaccinated, and booster-vaccinated persons.

resultsBased on a population of 982,047 adults with kidney disease, a total of 359,428 SARS-CoV-2 infections (Alpha: n = 7861, Delta: n = 27,868, Omicron: n = 323,699) were identified. Vaccination and booster vaccination were associated with benefits on rates of SARS-CoV-2 infection and subsequent 30-day mortality, with age- and gender-standardized rate ratios for SARS-CoV-2 infection of 0.24 (95% CI 0.21-0.28), 0.33 (95% CI 0.22-0.50), 0.32 (95% CI 0.19-0.54), 0.91 (95% CI 0.32-2.58), and 0.24 (95% CI 0.08-0.73) and age- and gender-standardized 30-day mortality differences of -1.5 (95% CI -1.7, -1.2), -5.8 (95% CI -7.1, -4.5), -12.4 (95% CI -15.3, -9.5), -16.9 (95% CI -21.9, -11.8), and -10.7 (95% CI -16.6, -4.8) for booster vaccinations compared with no vaccination for eGFR ≥ 60 mL/min/1.73 m

conclusionsVaccination and booster vaccination against SARS-CoV-2 were associated with benefits on rates of SARS-CoV-2 infections and associated 30-day mortality risk irrespective of kidney function.

Indexed as

COVID-19COVID-19 VaccinesRenal Insufficiency, ChronicVaccinationAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesSARS-CoV-2Unvaccinated PersonsCOVID-19 Vaccineschronic kidney diseaseCOVID-19eGFRmortalityvaccination

Identifiers

PMID41286258
PMCPMC13241337

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.