Evidence map›Paper›PMID 41286233›Full record

ArticleScientific reports2025

Hemodynamic characteristics and drug deposition in cerebral aneurysm sac.

Digamber Singh, Abdullah Y Usmani, Rajeev Kumar Upadhyay

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Digamber SinghAlliance University Bengaluru, Bengaluru, Karnataka, 562106, India. digamber35@gmail.com.
Abdullah Y UsmaniDepartment of Mechanical Engineering, Zakir Hussain College of Engineering and Technology, Aligarh Muslim University, Aligarh, 202002, U.P, India.
Rajeev Kumar UpadhyayMechanical Engineering Dept. KNIT Sultanpur, Sultanpur, 228118, U.P, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient-specific cerebral aneurysms exhibit complex hemodynamics insights that influence thrombus formation, wall remodeling, and therapeutic delivery. The article presents a high-fidelity, multi-parametric CFD analysis of nine distinct aneurysm cases using 3-D model-resolved meshes, non-Newtonian Casson rheology, and steady-state flow conditions. Further, the Lagrangian particle tracking was employed to assess drug transport and hemodynamic metrics such as WSS and normalized residence time (NRT) were evaluated, along with vortex dynamics, indicators including helicity (H) and Q criterion to characterize rotational flow structures. Results reveal that narrowed neck models (m

Indexed as

Aneurysm, RupturedHemodynamicsIntracranial AneurysmIntracranial ThrombosisModels, CardiovascularHemorheologyHumansDrug depositionHemodynamicsMicrothrombusNon-NewtonianRupture riskWall shear stress

Identifiers

PMID41286233
PMCPMC12644918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.