Evidence map›Paper›PMID 41286182›Full record

ReviewThe Saudi dental journal2025

Advances in adjunctive root coverage techniques: a narrative review of laser therapy, hyaluronic acid, and nanomaterials.

Helmi M A Khatib

Abstract readReview
In one paragraph

Review in The Saudi dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Helmi M A KhatibFaculty of Dentistry, An-Najah National University, Nablus, Palestine. hilmi.khatib@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gingival recession (GR) is a prevalent condition characterized by the apical migration of the gingival margin, leading to root exposure and aesthetic and functional challenges. While conventional surgical techniques like coronally advanced flaps and connective tissue grafts are considered the gold standard for root coverage, these methods are limited by patient morbidity and inconsistent long-term outcomes. Adjunctive strategies such as laser therapy, hyaluronic acid (HA), and nanomaterials have been introduced to improve clinical results. This narrative review explores the rationale and clinical relevance of these adjunctive therapies in root coverage procedures. This narrative review (2017-2025) critically examines laser therapy, hyaluronic acid, and nanomaterials as adjuncts in surgical root coverage. Human studies were prioritized, with preclinical data included for nanomaterials. Biological mechanisms, clinical efficacy, and limitations were analyzed to provide a comparative perspective and highlight future research directions in periodontal regeneration. The literature indicates that while these therapies offer distinct benefits, their clinical effectiveness remains inconclusive. Laser therapy aids tissue healing, HA offers regenerative effects, and nanomaterials facilitate bioactive delivery. However, clinical evidence on long-term efficacy, especially in achieving consistent root coverage, remains limited. Adjunctive therapies such as laser therapy, HA, and nanomaterials show promise in improving outcomes for gingival recession treatment. However, further high-quality clinical trials are needed to validate their efficacy, safety, and long-term results.

Indexed as

Adjunctive therapiesGingival recessionHyaluronic acidLaser therapyNanomaterialsPeriodontal plastic surgery

Identifiers

PMID41286182
PMCPMC12644272

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.