Evidence map›Paper›PMID 41286126›Full record

ArticleCommunications medicine2025

A comprehensive study of cognitive control in healthy aging.

Sarah De Pue, Hans Stuyck, Céline R Gillebert, Eva Dierckx, Eva Van den Bussche

Abstract read
In one paragraph

Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah De PueBrain & Cognition, Leuven Brain Institute, KU Leuven, Leuven, Belgium. sarah.depue@kuleuven.be.ORCID http://orcid.org/0000-0003-2238-2137
Hans StuyckBrain & Cognition, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Céline R GillebertBrain & Cognition, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Eva DierckxPersonality and Psychopathology, Vrije Universiteit Brussel, Brussels, Belgium.
Eva Van den BusscheBrain & Cognition, Leuven Brain Institute, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-1894-9380

Funding

Fonds Wetenschappelijk Onderzoek (Research Foundation Flanders) 11J1221N
6 · The paper itself

Abstract

backgroundDeclines in cognitive control impact older adults' daily life and independence. Cognitive control frameworks distinguish different subcomponents, such as inhibition, updating, shifting, proactive and reactive control. A comprehensive overview of how these subcomponents develop in aging is lacking, with research typically focusing on small samples treated as a homogenous age group, targeting a single subcomponent, or using heterogenous tasks across studies. The aim of the current study was therefore to provide a more comprehensive overview of cognitive control in aging, studying multiple subcomponents in a large sample including different age cohorts.

methodsIn the current study, young adults (N = 75) and three cohorts of older adults (N = 231) completed an extensive test battery assessing multiple subcomponents of cognitive control, including response inhibition, interference control, updating, shifting, and reactive and proactive control. Linear mixed models and generalized linear mixed models were used to compare cognitive control performance between the age groups.

resultsOur results show improved response inhibition and interference control in older compared to young adults. Updating and shifting decrease with age, while proactive control remains preserved in older adults.

conclusionsThese findings show that changes in cognitive control subcomponents follow different onsets and trajectories, highlighting the importance of including them in cognitive aging research. While some cognitive control functions decline, others seem to be preserved or even improve with age. Longitudinal follow-up studies can help uncover inter- and intra-individual changes in subcomponents with aging.

Identifiers

PMID41286126
PMCPMC12764825

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.