Evidence map›Paper›PMID 41286058›Full record

ArticleScientific reports2025

Development of biodegradable Mg-Zn-Zr-based temporary implant materials through multidirectional forging and laser shock peening.

S Aditya Kudva, Gajanan Anne, Prakash Kumar, Ashwini Prabhu, S Ramesh

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

S Aditya KudvaDepartment of Mechanical Engineering, Research Center, Shri Madhwa Vadiraja Institute of Technology and Management, Bantakal, Udupi, Visvesvaraya Technological University (VTU), Belagavi, 590018, Karnataka, India.
Gajanan AnneDepartment of Mechanical Engineering, Research Center, Shri Madhwa Vadiraja Institute of Technology and Management, Bantakal, Udupi, Visvesvaraya Technological University (VTU), Belagavi, 590018, Karnataka, India. gajanan.anne@manipal.edu.
Prakash KumarUnivLabs Technologies Private Limited, Gurugram, 122003, Haryana, India.
Ashwini PrabhuYenepoya Research Centre, Yenepoya (Deemed to be University), Deralakatte, Mangalore, 575018, Karnataka, India.
S RameshSchool of Computer Science and Engineering, RV University, Bangaluru, 560059, India.

Funding

Manipal Academy of Higher Education, Manipal
6 · The paper itself

Abstract

Biodegradable magnesium alloys have been a fascinating but challenging research arena, as development of such alloys for clinical applications can be a game changer in orthopedics, while controlling the degradation rate of magnesium alloys in physiological conditions is an area of concern. In quest of solution to the existing issue, this study involves development of biodegradable Mg-4Zn-0.6Zr alloy subjected to multidirectional forging (MDF) for bulk property improvement and laser shock peening for surface property improvement. The MDF process was carried out for 5 passes and resulted in significant grain refinement of the alloy from 180 ± 12 μm to 16 ± 5 μm after 5 MDF passes as observed through Scanning Electron Microscope (SEM), Laser Shock Peening (LSP) induced further grain refinement in nano scale as evident through Transmission Electron Microscope (TEM). After 5 MDF passes, the average microhardness of the alloy increased to 101.8 HV due to grain refinement and strain, further rising to 112.6 HV post-LSP from additional grain refinement and dislocations, while tensile tests showed a 141% improvement in Ultimate Tensile Strength (UTS) after 3 MDF passes compared to the homogenized state. The results of the electrochemical corrosion tests indicated that both MDF and LSP resulted in the least corrosion rate, about a factor of one order of magnitude reduction in comparison to the homogenized sample. The key results including mechanical properties, corrosion behaviour in Hanks Balanced Salt Solution and cytotoxicity evaluation employing MG-63 osteoblast-like cells suggest that the considered Mg-4Zn-0.6Zr alloy could be a worthy candidate to be further explored as a bioimplant material.

Indexed as

Absorbable ImplantsAlloysBiocompatible MaterialsMagnesiumZincZirconiumCell LineHumansLasersMaterials TestingMicroscopy, Electron, ScanningOsteoblastsSurface PropertiesTensile StrengthAlloysBiocompatible MaterialsMagnesiumZincZirconiumBiodegradable mg based alloyCytotoxicityImplant materialsLaser shock peeningMultidirectional forging

Identifiers

PMID41286058
PMCPMC12645033

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.