Evidence map›Paper›PMID 41286031›Full record

ReviewNature reviews. Gastroenterology & hepatology2026

Liver disease in people living with HIV infection: a changing landscape.

Frances Lee, Meena B Bansal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A people-first, systems-oriented approach to liver disease in HIV infection.Nature reviews. Gastroenterology & hepatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Frances LeeDivision of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
Meena B BansalDivision of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA. meena.bansal@mssm.edu.ORCID http://orcid.org/0000-0002-7501-2191

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As persons living with human immunodeficiency virus (HIV) infection are living longer, non-AIDS-related mortality continues to rise, with liver disease being one of the most common causes. This Review provides a synopsis of the current burden of liver diseases, ranging from viral hepatitis to metabolic dysfunction-associated steatotic liver disease to liver cancer, and discusses the barriers and challenges to screening and treatment as well as cofactors contributing to increasing disease burden. A brief insight is provided on the potential molecular mechanisms driving hepatic inflammation and fibrosis in persons living with HIV. Given the effect of direct-acting antivirals on hepatitis C virus infection and suppressive treatment for hepatitis B virus infection, special attention is drawn to the emergence of metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis in this population, focusing on factors related to the increasing prevalence of relevant comorbidities, the role of antiretroviral therapy, and HIV-specific factors in driving liver fibrosis progression.

Indexed as

HIV InfectionsLiver DiseasesComorbidityHumansLiver Cirrhosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.