Evidence map›Paper›PMID 41286018›Full record

ArticleCommunications biology2025

Quadruple parametric optical mapping to measure cardiac metabolism-excitation-contraction coupling.

Amber Mills, Sharon Ann George

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amber MillsDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-8898-7780
Sharon Ann GeorgeDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA. sageorge@pitt.edu.ORCID http://orcid.org/0000-0001-9003-1158

Funding

American Heart Association (American Heart Association, Inc.) 935807American Heart Association-American Stroke Association 935807
6 · The paper itself

Abstract

Metabolism-excitation-contraction coupling (MECC) refers to the interdependent facets of cardiac physiology working synchronously to generate each heartbeat. Simultaneous imaging of MECC parameters: transmembrane potential (V

Indexed as

Excitation Contraction CouplingHeartMyocardiumOptical ImagingAnimalsCalciumFlecainideMaleMembrane PotentialsNADNifedipineRatsCalciumFlecainideNADNifedipine

Identifiers

PMID41286018
PMCPMC12749837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.