Evidence map›Paper›PMID 41285981›Full record

ArticleScientific reports2025

CT-based body composition and its demographic and clinical associations in women aged 20 to 40 with non-metastatic breast cancer.

Ana P T Fayh, Ingryd F M Soares, Glaucia M C Ferreira, Ana Lucia Miranda, Agnes D L Bezerra, Galtieri O C Medeiros, Jarson P Costa-Pereira, Carla M Prado, M Cristina Gonzalez, Sara M M L Verde

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana P T FayhDepartment of Nutrition, Federal University of Health Science of Porto Alegre, Porto Alegre, Brazil. ana.fayh@ufcspa.edu.br.
Ingryd F M SoaresPostgraduate Program in Nutrition and Health, State University of Ceara, Fortaleza, Brazil.
Glaucia M C FerreiraGraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Ana Lucia MirandaGraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Agnes D L BezerraGraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Galtieri O C MedeirosGraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Jarson P Costa-PereiraPostgraduate Program in Nutrition and Public Health, Department of Nutrition, Federal University of Pernambuco, Recife, PE, Brazil.
Carla M PradoDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.
M Cristina GonzalezPostgraduate Program in Nutrition and Food, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Sara M M L VerdePostgraduate Program in Nutrition and Health, State University of Ceara, Fortaleza, Brazil.

Funding

Brazil (Finance Code 001)Brazilian National Council for Scientific and Technological Development (CNPq)Canada Research Chairs ProgramCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
6 · The paper itself

Abstract

This cross-sectional study investigated the relationship between CT-based body composition parameters and demographic and clinical factors in young women (< 40 years) with non-metastatic (I–III) breast cancer. Data on anthropometry, sociodemographic characteristics, and tumor profiles were extracted from medical records. Body composition was assessed using CT scans at the third lumbar vertebra (L3), measuring skeletal muscle cross-sectional area (SM), skeletal muscle index (SMI), skeletal muscle radiodensity (SMD), visceral adipose tissue (VAT), and subcutaneous adipose tissue (SAT). A total of 173 patients were included (mean age: 33.8 ± 4.1 years). Most women had stage III tumors and hormone receptor-positive status. Higher VAT levels were associated with older age (P = 0.001). A higher education level was associated with higher SAT values. Women with invasive ductal carcinoma or positive estrogen receptor status were less likely to have high VAT. Patients with high VAT and SAT had higher BMI, SM, and SMI, and lower SMD (all P < 0.005). Our findings suggest that SAT and VAT are associated with educational level and tumor aggressiveness, respectively, highlighting the importance of monitoring body composition as part of clinical care in young women with breast cancer.

Indexed as

Body CompositionBreast NeoplasmsTomography, X-Ray ComputedAdultCross-Sectional StudiesFemaleHumansIntra-Abdominal FatMuscle, SkeletalSubcutaneous FatYoung AdultBody compositionSkeletal muscle massSkeletal muscle radiodensitySubcutaneous adipose tissueTreatable breast cancerVisceral adipose tissue

Identifiers

PMID41285981
PMCPMC12749292

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.