Evidence map›Paper›PMID 41285501›Full record

ArticleBMJ open2025

Perceptions of an AI-based clinical decision support tool for prescribing in multiple long-term conditions: a qualitative study of general practice clinicians in England.

Alexander d'Elia, Simon George Morris, Jennifer Cooper, Krishnarajah Nirantharakumar, Thomas Jackson, Tom Marshall, Leah Fitzsimmons, Louise J Jackson, Francesca Crowe, Shamil Haroon and 2 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander d'EliaCollege of Medicine and Health, University of Birmingham Institute of Applied Health Research, Birmingham, UK a.delia.1@bham.ac.uk.ORCID http://orcid.org/0000-0001-8735-9689
Simon George MorrisUniversity of Birmingham Institute of Applied Health Research, Birmingham, UK.
Jennifer CooperUniversity of Birmingham Institute of Applied Health Research, Birmingham, UK.
Krishnarajah NirantharakumarUniversity of Birmingham Institute of Applied Health Research, Birmingham, UK.ORCID http://orcid.org/0000-0002-6816-1279
Thomas JacksonUniversity of Birmingham Institute of Inflammation and Ageing, Birmingham, UK.
Tom MarshallUniversity of Birmingham Unit of Public Health Epidemiology and Biostatistics, Birmingham, UK.ORCID http://orcid.org/0000-0001-9277-5214
Leah FitzsimmonsUniversity of Birmingham Institute of Applied Health Research, Birmingham, UK.
Louise J JacksonUniversity of Birmingham Health Economics Unit, Birmingham, UK.
Francesca CroweUniversity of Birmingham Institute of Applied Health Research, Birmingham, UK.ORCID http://orcid.org/0000-0003-4026-1726
Shamil HaroonUniversity of Birmingham Institute of Applied Health Research, Birmingham, UK.ORCID http://orcid.org/0000-0002-0096-1413
Sheila GreenfieldUniversity of Birmingham Institute of Applied Health Research, Birmingham, UK.ORCID http://orcid.org/0000-0002-8796-4114
Ellie HathawayUniversity of Birmingham Institute of Applied Health Research, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI)-based clinical decision support systems (CDSSs) are currently being developed to aid prescribing in primary care. There is a lack of research on how these systems will be perceived and used by healthcare professionals and subsequently on how to optimise the implementation process of AI-based CDSSs (AICDSSs).

objectivesTo explore healthcare professionals' perspectives on the use of an AICDSS for prescribing in co-existing multiple long-term conditions (MLTC), and the relevance to shared decision making (SDM).

designQualitative study using template analysis of semistructured interviews, based on a case vignette and a mock-up of an AICDSS.

settingHealthcare professionals prescribing for patients working in the English National Health Service (NHS) primary care in the West Midlands region.

participantsA purposive sample of general practitioners/resident doctors (10), nurse prescribers (3) and prescribing pharmacists (2) working in the English NHS primary care.

resultsThe proposed tool generated interest among the participants. Findings included the perception of the tool as user friendly and as a valuable complement to existing clinical guidelines, particularly in a patient population with multiple long-term conditions and polypharmacy, where existing guidelines may be inadequate. Concerns were raised about integration into existing clinical documentation systems, medicolegal aspects, how to interpret findings that were inconsistent with clinical guidelines, and the impact on patient-prescriber relationships. Views differed on whether the tool would aid SDM.

conclusionAICDSSs such as the OPTIMAL tool hold potential for optimising pharmaceutical treatment in patients with MLTC. However, specific issues related to the tool need to be addressed and careful implementation into the existing clinical practice is necessary to realise the potential benefits.

Indexed as

Artificial IntelligenceAttitude of Health PersonnelDecision Support Systems, ClinicalChronic DiseaseDecision Making, SharedEnglandFemaleGeneral PractitionersHumansInterviews as TopicMalePractice Patterns, Physicians'Primary Health CareQualitative ResearchState MedicineArtificial IntelligenceMultimorbidityPrimary Health CareQUALITATIVE RESEARCH

Identifiers

PMID41285501
PMCPMC12645610

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.