Evidence map›Paper›PMID 41285498›Full record

ArticleBMJ open2025

Effectiveness of rapid verbal persuasion in promoting herpes zoster vaccination among older adults in China: study protocol of a two-arm randomised controlled trial.

Zizhen Huang, Qing-Qing Li, Zhixiang Tang, Siyuan Liu, Dongmei Zhong, Qunzhi Sun, Junyao Wang, Xiaoshan Huang, Yuting Qiu, Junlin Zhu and 8 more

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Zizhen Huang *Acacia Lab for Implementation Science, School of Health Management, Southern Medical University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0009-0000-7732-1468
Qing-Qing Li *Southern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Zhixiang Tang *Department of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China.
Siyuan LiuAcacia Lab for Implementation Science, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Dongmei ZhongSouthern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0000-0002-0886-6445
Qunzhi SunDepartment of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China.
Junyao WangDepartment of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China.
Xiaoshan HuangDepartment of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China.
Yuting QiuDepartment of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China.
Junlin ZhuAcacia Lab for Implementation Science, School of Health Management, Southern Medical University, Guangzhou, Guangdong, China.
Xiaoqing ZhuAcacia Lab for Implementation Science, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Run WangSouthern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0000-0002-1743-6025
Wenjun HeSouthern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Rui ZhaoShenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China.
Mengjun ZhangShenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China.
Huanyuan LuoShenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China.
Changxia LuoDepartment of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China 13872790778@163.com.
Dong Roman XuSouthern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHerpes zoster (HZ) vaccinations effectively prevent HZ and may decrease dementia, but HZ vaccine uptake remains poor in China. Rapid verbal persuasion is an innovative intervention, in which physicians offered brief advice to encourage individuals to accept vaccination. This study aims to tailor this intervention to promote HZ vaccination among older adults. METHODS AND ANALYSIS: The proposed study will be a two-arm randomised controlled trial and conducted across four community health centres in Shenzhen, China. A total of 388 participants aged 50 and above will be recruited and assigned to either the intervention arm or the standard-care arm. The primary outcome will be first-dose uptake, recorded within 3 weeks after intervention. The primary outcome will be calculated for each arm and compared using χ ETHICS AND DISSEMINATION: This trial has been approved by the Ethics Committee of Southern Medical University (Ethical Approval (2024) No. 90). Our findings will be disseminated to patients, healthcare providers and stakeholders through outreach activities and published in peer-reviewed journals, as well as presented in scientific conferences to inform future research or evidence-based practices for public health promotion. TRIAL REGISTRATION NUMBER: Chinese Clinical Trial Registry (No. ChiCTR2500100798). Registered on 15 April 2025.

Indexed as

Health PromotionHerpes ZosterHerpes Zoster VaccinePersuasive CommunicationVaccinationAgedChinaFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicHerpes Zoster VaccineHealth ServicesRandomized Controlled TrialVaccination

Identifiers

PMID41285498
PMCPMC12645612

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.