Evidence map›Paper›PMID 41285426›Full record

ReviewRenal failure2025

The molecular mechanisms and therapeutic potential of p53 in kidney injury repair: a perspective on the p53alpha/delta133p53alpha signaling axis.

Jiayan Fan, Yitian Guo, Guanhua Cui, Li Qiu, Nieke Zhang, Shuchun Tao, Hang Wu, Guangyuan Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiayan FanSchool of Basic Medical Sciences, Shandong Second Medical University, Weifang, China.
Yitian GuoDepartment of Urology, Zhongda Hospital Southeast University, Nanjing, China.
Guanhua CuiSchool of Basic Medical Sciences, Shandong Second Medical University, Weifang, China.
Li QiuSchool of Basic Medical Sciences, Shandong Second Medical University, Weifang, China.
Nieke ZhangSchool of Medicine, Southeast University, Nanjing, China.
Shuchun TaoSchool of Medicine, Southeast University, Nanjing, China.
Hang WuDepartment of Rehabilitation Medicine, Zhongda Hospital Southeast University, Nanjing, China.
Guangyuan ZhangSchool of Basic Medical Sciences, Shandong Second Medical University, Weifang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Kidney InjuryTumor Suppressor Protein p53AnimalsApoptosisAutophagyHumansProtein IsoformsReperfusion InjurySignal TransductionProtein IsoformsTumor Suppressor Protein p53delta133p53kidney injuryp53alphap53 isoformsTP53

Identifiers

PMID41285426
PMCPMC12646098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.