Evidence map›Paper›PMID 41284913›Full record

Trial reportThe Gerontologist2025

"Taking Charge" after a diagnosis of cognitive impairment or dementia: a randomized controlled trial.

Miia Rahja, Harry McNaughton, Maria Crotty, Aarti Gulyani, Qunyan Xu, Owen Davies, Elita Santosaputri, Kate Laver

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Gerontologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miia RahjaFlinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Adelaide, South Australia, Australia.ORCID 0000-0003-0845-5459
Harry McNaughtonMedical Research Institute of New Zealand, Wellington, New Zealand.
Maria CrottyFlinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Adelaide, South Australia, Australia.
Aarti GulyaniFlinders University, College of Nursing and Health Sciences, Caring Futures Institute, Adelaide, South Australia, Australia.ORCID 0000-0003-3388-1476
Qunyan XuFlinders University, College of Nursing and Health Sciences, Caring Futures Institute, Adelaide, South Australia, Australia.
Owen DaviesDivision of Rehabilitation, Aged and Palliative Care, Southern Adelaide Local Health Network, Adelaide, South Australia, Australia.
Elita SantosaputriDivision of Rehabilitation, Aged and Palliative Care, Southern Adelaide Local Health Network, Adelaide, South Australia, Australia.
Kate LaverDivision of Rehabilitation, Aged and Palliative Care, Southern Adelaide Local Health Network, Adelaide, South Australia, Australia.

Funding

Dementia Centre for Research Collaboration, AustraliaFlinders FoundationHospital Research Foundation
6 · The paper itself

Abstract

BACKGROUND AND

objectivesSelf-directed programs can steer positive trajectories after life-changing health events. This study evaluated if one such program (Take Charge) could improve quality of life (QoL) after diagnosis of mild cognitive impairment (MCI) or mild dementia compared with lifestyle education. RESEARCH DESIGN AND

methodsTwo-arm, open-label, randomized controlled trial including people with MCI or mild dementia in Adelaide, Australia. Participants were assigned to Take Charge intervention (n = 80) or control group (lifestyle education with waitlist option) (n = 80). The primary outcome was QoL measured using the Physical Component Summary (PCS) score of the Short Form 36 (SF-36) at three months following baseline comparing Take Charge to control. Secondary outcomes included the mental component summary (MCS) score of SF-36, hope, mood (depression scale), and activity engagement at three and six months. A subset of participants participated in an interview about their experiences with Take Charge.

resultsParticipants had a mean age of 79.6 years (SD 7.2) and 51.2% were female. The mean Mini-Mental State Examination score was 24.2 (SD 3.2). No significant differences were found in PCS scores between groups at three months (-0.53; 95% CI: -4.23, 3.17; p = .78). However, interviews suggested that those actively engaged in Take Charge felt more positive about the future. DISCUSSION AND IMPLICATIONS: There was no significant difference between the Take Charge and control groups, and Take Charge did not improve physical health-related QoL for people living with MCI or mild dementia. More work is needed to establish the appropriateness and efficacy of self-directed programs for this population.

Indexed as

Cognitive DysfunctionDementiaQuality of LifeAgedAged, 80 and overFemaleHumansLife StyleMaleDementiaMild cognitive impairmentRandomized controlled trialSelf-managementTake Charge

Identifiers

PMID41284913
PMCPMC12742850

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.