ArticleThe Plant journal : for cell and molecular biology2025
Rewiring of LEUNIG_HOMOLOG interaction networks marks regulatory shifts from meristem to organ growth in Arabidopsis flowers.
Article in The Plant journal : for cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- 800 million years of co-evolution in the green plant lineage: the case of LEUNIG and SEUSS transcriptional co-regulators.Molecular biology and evolution · 2026Article
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12 authors.
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Abstract
LEUNIG (LUG) and LEUNIG_HOMOLOG (LUH) are Groucho/Tup1-type transcriptional co-regulators in Arabidopsis thaliana that act redundantly across multiple developmental and environmental response pathways. Their specific contributions to flower development, however, have remained unclear due to embryonic lethality of double mutants. Here, we show that LUH associates with distinct sets of transcription factors and chromatin-associated proteins in a developmentally dynamic manner. Chromatin occupancy and protein interactions shift from a meristem-focused network during early floral patterning to an organogenesis-oriented state as primordia initiate and expand. Reduced promoter-proximal LUH binding coincides with this proliferative phase, suggesting a transient reconfiguration of LUH activity. By later stages, LUH activity is amplified alongside organ differentiation programs. Together with LUG, LUH modulates gene expression programs that are essential for establishing floral organ patterning. These findings reveal how dynamic co-regulator assemblies contribute to the temporal coordination of growth and spatial pattern formation in Arabidopsis flowers.
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