Evidence map›Paper›PMID 41284832›Full record

Trial reportPersonality disorders2026

Obsessive-compulsive personality disorder in radically open dialectical behavior therapy for treatment-refractory depression.

Molly Fennig Steinhoff, Julian Baudinet, Roelie J Hempel, Rebecca Tillman, Thomas R Lynch, Kirsten E Gilbert

Abstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Personality disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Molly Fennig SteinhoffDepartment of Psychological & Brain Sciences, Washington University in St. Louis.ORCID 0000-0002-8402-0492
Julian BaudinetMaudsley Centre for Child and Adolescent Eating Disorders (MCCAED), Michael Rutter Centre, Maudsley Hospital.ORCID 0000-0002-7840-4158
Roelie J HempelRO DBT Online B.V.
Rebecca TillmanDepartment of Psychiatry, Washington University in St. Louis.
Thomas R LynchSchool of Psychology, University of Southampton.
Kirsten E GilbertDepartment of Psychiatry, Washington University in St. Louis.

Funding

WUSTL Transdisciplinary Pre- and Postdoctoral Training Program in Obesity and Cardiovascular DiseaseT32HL130357 · NHLBI · WASHINGTON UNIVERSITY · PI WILFLEY, DENISE ELLA · 2016 to 2025
$4.3M
Neural and behavioral trajectories of the overcontrolled phenotype: Associations with development, social context and psychiatric symptoms in early childhoodR01MH126984 · NIMH · WASHINGTON UNIVERSITY · PI Kirsten Gilbert · 2022 to 2026
$3.4M
Developmental pathways and treatment of OCD and anorexia: the role heightened performance monitoring and overcontrolF31MH137979 · NIMH · WASHINGTON UNIVERSITY · PI Molly Fennig Steinhoff · 2025 to 2026
$83k
Efficacy and Mechanism Evaluation (EME) ProgramMRCNHLBI NIH HHSNHLBI NIH HHS T32 HL130357NIMH NIH HHSNIMH NIH HHS F31 MH137979NIMH NIH HHS R01 MH126984Taylor Family Institute for Innovative Psychiatric Research
6 · The paper itself

Abstract

Obsessive-compulsive personality disorder (OCPD) is commonly comorbid with major depressive disorder, and their comorbidity is associated with worsened outcomes and treatment refraction. Radically open dialectical behavior therapy (RO DBT) is a novel transdiagnostic psychosocial intervention. RO DBT targets OCPD-related traits (e.g., maladaptive perfectionism, inflexibility) and has been theorized as an OCPD treatment. This study examined RO DBT efficacy for treatment-refractory depression (TRD), with and without comorbid OCPD. RefraMED was a multisite randomized controlled trial of treatment as usual (TAU) versus RO DBT + TAU for TRD (

Indexed as

Compulsive Personality DisorderDepressive Disorder, Treatment-ResistantDialectical Behavior TherapyMajor Depressive DisorderOutcome Assessment, Health CareAdultComorbidityFemaleHumansMaleMiddle Aged

Identifiers

PMID41284832
PMCPMC12646503

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.