Evidence map›Paper›PMID 41284693›Full record

ArticlePloS one2025

Effects of dysmenorrhea on work productivity and quality of life in Japanese women: A large-scale web-based cross-sectional study.

Maika Nariai, Osamu Wada-Hiraike, Eri Maeda, Masayo Matsuzaki, Mayuyo Mori-Uchino, Maho Furukawa, Yuki Enomoto, Hiromi Ga, Risa Takai, Miyuki Harada and 2 more

Erratum issuedAbstract read
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In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Maika NariaiDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-0327-2928
Osamu Wada-HiraikeDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3458-6711
Eri MaedaDepartment of Public Health, Faculty of Medicine, Hokkaido University, Sapporo, Japan.
Masayo MatsuzakiDepartment of Reproductive Health Nursing, Graduate School of Health Care Sciences, Institute of Science Tokyo, Tokyo, Japan.
Mayuyo Mori-UchinoDepartment of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Maho FurukawaDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0003-9634-7024
Yuki EnomotoDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiromi GaDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Risa TakaiDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Miyuki HaradaDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Yutaka OsugaDepartment of Obstetrics and Gynecology, Teikyo University School of Medicine, Tokyo, Japan.
Yasushi HirotaDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-0241-9780

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

research questionHow significant is the impact of dysmenorrhea on work productivity and quality of life (QoL) among Japanese women?.

methodsThis large-scale cross-sectional study was conducted using a web-based self-report questionnaire administered via a smartphone application (LunaLuna). The Work Productivity and Activity Impairment Questionnaire: General Health (WPAI-GH) and the SF-36v2 health survey were used to assess work productivity and health-related QoL, respectively. Work productivity and health-related QoL were compared between the severe and non-severe groups as defined by the dysmenorrhea score, which assesses the severity of menstrual pain, its impact on daily activities, and medication use. A multiple regression analysis was performed to estimate the magnitude of the effect of dysmenorrhea on work productivity and health-related QoL after adjusting for confounding factors.

resultsIn total, 2,555 women were included in the analysis. Among them, 2064 women completed the dysmenorrhea score questionnaire, and 902 (43.7%) participants with a dysmenorrhea score of ≥3 were categorized as the severe group. The median overall work impairment was 16% higher in the severe dysmenorrhea group than in the non-severe dysmenorrhea group. In the multiple regression analysis, despite adjusting for confounding factors, the severity of dysmenorrhea remained a significant predictor of impaired absenteeism; presenteeism; overall work impairment; activity impairment; and reduced physical, mental, and social QoL. Additionally, low annual household income (<5,000,000 yen) was a significant predictor of reduced work productivity and lower mental and social QoL.

conclusionsThe severity of dysmenorrhea significantly affects the work productivity and quality of life of Japanese women. A dysmenorrhea score of ≥3 as a threshold for treatment eligibility may be a useful and potentially valid criterion. The application of a dysmenorrhea score may facilitate the screening of dysmenorrhea in clinical practice.

Indexed as

DysmenorrheaEfficiencyQuality of LifeAdultCross-Sectional StudiesEast Asian PeopleFemaleHumansInternetJapanMiddle AgedSelf ReportSurveys and QuestionnairesYoung Adult

Identifiers

PMID41284693
PMCPMC12643315

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.