Evidence map›Paper›PMID 41284537›Full record

ArticleJournal of affective disorders2026

Positive psychological well-being and psychological distress in higher education students.

Jeffrey A Lam, Veri Seo, Lindsay N Overhage, Emma P Keane, Alexandra R Dobbins, Melisa D Granoff, Ana M Progovac, Hermioni L Amonoo

Abstract read
In one paragraph

Article in Journal of affective disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeffrey A LamDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. Electronic address: jelam@cha.harvard.edu.
Veri SeoDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Lindsay N OverhageDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Emma P KeaneDepartment of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA.
Alexandra R DobbinsDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA.
Melisa D GranoffDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Ana M ProgovacInstitute of Excellence in Health Equity and Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
Hermioni L AmonooDepartment of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Department of Supportive Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Funding

Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
MD-PhD Training Program in Aging and the Social/Behavioral SciencesT32AG051108 · NIA · HARVARD MEDICAL SCHOOL · PI MCWILLIAMS, JOHN MICHAEL · 2015 to 2025
$2.1M
NIA NIH HHS T32 AG051108NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

backgroundPositive psychology well-being constructs like flourishing are important predictors of health and quality of life. However, few studies have examined the association between flourishing and psychological distress (i.e., depression and anxiety). We investigated the association between flourishing and psychological distress symptoms among higher education students.

methodsWe analyzed cross-sectional survey data from 60,386 students aged 18-34 in the United States (Healthy Minds Study 2022-2023). Flourishing was measured using the Flourishing Scale, while symptoms of depression and anxiety were assessed using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 scales, respectively. Associations between flourishing and psychological distress were examined using multiple logistic regression models, adjusting for age, gender identity, race/ethnicity, financial stress, and self-reported mental health treatment.

resultsOf the 60,386 participants included the mean age was 21.7 (SD = 3.6). Most participants were female (68.3 %) and White (55.6 %). Among individuals with significant symptoms of depression or anxiety, 13.7 % and 17.7 % were classified as flourishing (Flourishing Scale ≥48), respectively. Participants with significant symptoms of depression (OR: 0.23; CI: 0.22-0.25) or anxiety (OR: 0.56; CI: 0.54-0.59) were less likely to be classified as flourishing than those without significant symptoms.

conclusionFlourishing is possible within psychological distress. These results suggest the importance of assessing both positive psychological well-being and psychological distress to understand student mental health. While reducing symptoms of psychological distress is crucial, enhancing positive psychological well-being should also be prioritized as part of mental health treatment.

Indexed as

AnxietyDepressionPsychological DistressQuality of LifeStress, PsychologicalStudentsAdolescentAdultCross-Sectional StudiesFemaleHumansMaleMental HealthPsychological Well-BeingSurveys and QuestionnairesUnited StatesAnxietyDepressionFlourishingPositive psychologyStudent mental health

Identifiers

PMID41284537
PMCPMC13105321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.