ArticleEndocrine connections2025
Kidney stone recurrence in hypercalcemic and normocalcemic primary hyperparathyroidism without parathyroidectomy.
Article in Endocrine connections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aimed to compare the differences in kidney stone recurrence between typical primary hyperparathyroidism (TPHPT) and normocalcemic primary hyperparathyroidism (NPHPT) patients who did not receive parathyroidectomy (PTX) treatment. Materials and methods: We conducted a retrospective analysis of patients hospitalized for surgical management of kidney stones between September 2015 and March 2023. Patients' demographic data, blood test parameters, stone parameters, and surgical interventions were collected. Based on serum calcium and parathyroid hormone (PTH) levels, patients were categorized into TPHPT, NPHPT, and control groups. Postoperative stone recurrence was assessed during follow-up. Results: A total of 288 patients (139 males and 149 females) were analyzed, with 96 patients in each group. PTH and serum calcium levels were significantly higher in the TPHPT group than in both NPHPT and control groups (P < 0.001). The recurrence probability of kidney stones after surgery was higher in patients with both TPHPT and NPHPT than in the control group (42.7 vs 19.8% and 36.5 vs 19.8%, P < 0.05, respectively). However, no significant difference was found between TPHPT and NPHPT groups (P > 0.05). After adjusting for covariates, the Cox regression analysis revealed that NPHPT was a risk factor for kidney stone recurrence (HR: 2.31, 95% CI: 1.26-4.26, P = 0.007). Conclusions: Patients with TPHPT and NPHPT who have not undergone PTX treatment both exhibit a higher recurrence rate of kidney stones, with no significant difference between the two groups. Nevertheless, clinicians should place more emphasis on the recurrence of kidney stones in patients with NPHPT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.