Evidence map›Paper›PMID 41284304›Full record

ArticleCritical care explorations2025

Ward-Based High-Flow Nasal Cannula Led by the Medical Emergency Team: A Pragmatic Model for Resource Stewardship.

Imran Khalid, Basel Ghurm Alshehri, Raafey Imran, Muhammad Ali Akhtar, Manahil Imran, Tabindeh Jabeen Khalid, Maryam Imran, Mohsin Iqbal

Abstract read
In one paragraph

Article in Critical care explorations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Imran KhalidDepartment of Critical Care, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.ORCID 0000-0001-9901-926
Basel Ghurm AlshehriDepartment of Critical Care, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Raafey ImranDepartment of Critical Care, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Muhammad Ali AkhtarDepartment of Medicine, Hurley Medical Center, Flint, MI.
Manahil ImranDepartment of Critical Care, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Tabindeh Jabeen KhalidDepartment of Critical Care, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Maryam ImranDepartment of Critical Care, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Mohsin IqbalIndiana University Health, Indianapolis, IN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-flow nasal cannula (HFNC) for acute hypoxemic respiratory failure is typically restricted to ICUs. We evaluated a ward-based, medical emergency team (MET)-supervised HFNC protocol (flow ≤ 40 L/min, Fio2 ≤ 0.40) with 2-/4-/8-hour nursing and respiratory therapist reassessments. Among 82 ward HFNC initiations (2021-2024), 38 (46%) required immediate ICU transfer (IMT) and 44 (54%) were Ward-Managed After MET (WMAM). Of WMAM patients, 18 transferred to ICU within 48 hours, and 26 remained on ward. WMAM patients accrued a median 1.46 ICU bed-days saved (interquartile range, 0.73-2.67); bootstrapped mean 1.63 (95% CI, 1.32-1.94), equivalent to 163 ICU days-saved per 100 initiations. Intubation (30% vs. 42%; p = 0.24) and 28-day mortality (32% vs. 39%; p = 0.47) were similar between WMAM and IMT; adjusted analyses were directionally consistent. Using an estimated $5,000 per ICU-day, cost avoidance was ≈$815,000 per 100 initiations. This MET-supervised model appears feasible, resource-sparing, and without apparent safety signal.

Indexed as

CannulaOxygen Inhalation TherapyRespiratory InsufficiencyAgedFemaleHumansIntensive Care UnitsMaleMiddle AgedPatient Care Teamhigh-flow nasal cannula therapyintensive care unit utilizationmedical emergency teampatient safetyrespiratory insufficiency

Identifiers

PMID41284304
PMCPMC12647524

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.