Evidence map›Paper›PMID 41284226›Full record

Trial reportHealth education research2025

Designing and evaluating a technology-based intervention to address deep ambivalence about COVID vaccination among people who inject drugs.

I D Aronson, R Quiles, A Cramer, C Fong, B Gibson, B Vargas-Estrella, S Stern, A S Bennett

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Health education research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

I D AronsonCenter for Technology-based Education and Community Health, NDRI-USA, 31 West 34th Street, New York, NY 10001, United States.ORCID 0000-0002-2238-3810
R QuilesCenter for Technology-based Education and Community Health, NDRI-USA, 31 West 34th Street, New York, NY 10001, United States.
A CramerCenter for Technology-based Education and Community Health, NDRI-USA, 31 West 34th Street, New York, NY 10001, United States.
C FongCenter for Technology-based Education and Community Health, NDRI-USA, 31 West 34th Street, New York, NY 10001, United States.
B GibsonOnPoint NYC, 104-106 E 126th St, New York, NY 10035, United States.
B Vargas-EstrellaOnPoint NYC, 104-106 E 126th St, New York, NY 10035, United States.
S SternOnPoint NYC, 104-106 E 126th St, New York, NY 10035, United States.
A S BennettSchool of Global Public Health, New York University, 708 Broadway, New York, NY 10003, United States.

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
Community Developed Technology-Based Messaging to Increase SARS-CoV-2 Vaccine Uptake Among People Who Inject DrugsR01DA054990 · NIDA · NEW YORK UNIVERSITY · PI ARONSON, IAN DAVID · 2021 to 2024
$2.4M
NIDA NIH HHS P30 DA011041NIDA NIH HHS P30 DA029926NIDA NIH HHS R01 DA054990NIH HHS R01DA054990
6 · The paper itself

Abstract

To encourage people who inject drugs to vaccinate against COVID-19, our research team collaborated with a harm reduction organization in East Harlem to create a multilevel, technology-based intervention that combined a brief (<6 minute) educational video with pre-post-test items measuring the likelihood of vaccination, attitudes, and vaccine-related heath literacy. A total of 545 participants completed the intervention; 45 vaccinated at the end of their first study visit. The remaining 500 were randomly assigned to two groups that were sent different text message configurations to examine which more effectively encouraged follow-up vaccination. The intervention group received Multimedia Messaging Service text messages featuring combinations of words and images, similar to frames of a graphic novel; the control group received Short Message Service texts consisting solely of words. Among those who did not vaccinate at first visit, 26 (7 intervention group and 19 control) vaccinated at follow-up. Greater vaccine-related knowledge (e.g. the vaccine does not contain a live virus) and positive vaccine attitudes were significantly associated with post intervention vaccination. Misinformation and misconceptions (i.e. vaccines are population control; vaccination is only for people who are already sick) emerged as powerful barriers to vaccination. Further research is warranted to address other forms of vaccine hesitancy among additional high-risk populations.

Indexed as

COVID-19COVID-19 VaccinesSubstance Abuse, IntravenousVaccinationVaccination HesitancyAdultFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedSARS-CoV-2Text MessagingCOVID-19 VaccinesCOVIDdrugsinjecttechnologyvaccine

Identifiers

PMID41284226
PMCPMC12642696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.