Evidence map›Paper›PMID 41284151›Full record

ArticleEJNMMI research2025

Neuromelanin-targeted

Hongyan Feng, Ning Tu, Ke Wang, Xiaowei Ma, Zhentao Zhang, Zhongchun Liu, Zhen Cheng, Lihong Bu

Abstract read
In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongyan FengNuclear Medicine and PET-CT/MRI Center, Renmin Hospital of Wuhan University, 99Zhangzhidong Road, Wuchang District, Wuhan, Hubei, 430060, China.
Ning TuNuclear Medicine and PET-CT/MRI Center, Renmin Hospital of Wuhan University, 99Zhangzhidong Road, Wuchang District, Wuhan, Hubei, 430060, China.
Ke WangNuclear Medicine and PET-CT/MRI Center, Renmin Hospital of Wuhan University, 99Zhangzhidong Road, Wuchang District, Wuhan, Hubei, 430060, China.
Xiaowei MaDepartment of Nuclear Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhentao ZhangDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Zhongchun LiuDepartment of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Zhen ChengState Key Laboratory of Drug Research, Molecular Imaging Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. zcheng@simm.ac.cn.
Lihong BuNuclear Medicine and PET-CT/MRI Center, Renmin Hospital of Wuhan University, 99Zhangzhidong Road, Wuchang District, Wuhan, Hubei, 430060, China. bulihongs@126.com.

Funding

Key Technologies Research and Development Program of China 2018YFC1314600the Medical Science Advancement Program of Wuhan University TFLC 2018001The National Natural Science Foundation of China 81871419The National Natural Science Foundation of China 82101548The National Natural Science Foundation of China U2267221
6 · The paper itself

Abstract

backgroundNeuromelanin is mostly located in dopaminergic neurons in the substantia nigra (SN) pars compacta, and can be detected by magnetic resonance imaging (MRI). It is a promising imaging-base biomarker for neurological diseases. We previously developed a melanin-specific probe N-(2-(diethylamino)-ethyl)-

results

conclusion

Indexed as

18F-P3BZANeuromelaninSequential PET/MRSubstantia nigraSWI

Identifiers

PMID41284151
PMCPMC12644372

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.