Evidence map›Paper›PMID 41284127›Full record

ArticleInternal and emergency medicine2025

Effect of point-of-care echocardiography by noncardiologists on patient management in acute chest pain.

Petr Grenar, Martin Jakl, Karel Mědílek, Jiří Nový, Jaromír Kočí, Jan Vaněk, Martina Čermáková, Jan M Horáček, Radek Pudil

Registry-linked trialAbstract read
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In one paragraph

Article in Internal and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05306730 (Echocardiography by Non-cardiologist in Early Management of Patients With Chest Pain), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05306730 naunknown statusnot on this map

Echocardiography by Non-cardiologist in Early Management of Patients With Chest Pain

TypeinterventionalSponsorUniversity of Defence, Faculty of Military Health SciencesRan2022 to 2024Enrolled430ConditionsCardiology, Acute Coronary Syndrome, EchocardiographyArmsECHOcardiography, Point-of-Care UZ
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Petr Grenar *Department of Military Internal Medicine and Military Hygiene, Military Faculty of Medicine, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
Martin Jakl *Department of Military Internal Medicine and Military Hygiene, Military Faculty of Medicine, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic. martin.jakl@unob.cz.ORCID http://orcid.org/0000-0003-4185-9439
Karel MědílekFirst Department of Medicine-Cardioangiology, Charles University Prague, Medical Faculty and University Hospital Hradec Kralove, Prague, Czech Republic.
Jiří NovýDepartment of Emergency Medicine, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
Jaromír KočíDepartment of Emergency Medicine, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
Jan VaněkDepartment of Military Internal Medicine and Military Hygiene, Military Faculty of Medicine, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
Martina ČermákováDepartment of Emergency Medicine, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
Jan M HoráčekDepartment of Military Internal Medicine and Military Hygiene, Military Faculty of Medicine, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
Radek PudilFirst Department of Medicine-Cardioangiology, Charles University Prague, Medical Faculty and University Hospital Hradec Kralove, Prague, Czech Republic.

Funding

lékařská fakulta Univerzity Karlovy Cooperatiolékařská fakulta Univerzity Karlovy research area CARD.Ministerstvo Obrany České Republiky DZRO-FVZ22-KLINIKA II
6 · The paper itself

Abstract

As point-of-care echocardiography (POCE) has expanded beyond cardiology into general emergency medical practice, there has been a lack of standardized, evidence-based imaging protocols and training, thus leading to challenges with respect to the quality of cardiac imaging for acute cardiovascular syndromes. The ENDEMIC study aims to assess the effectiveness of POCE based on structured training for noncardiologists on the management of patients with acute chest pain in emergency departments. A total of 150 patients presenting with acute chest pain possibly of cardiovascular aetiology were enrolled in this prospective randomized clinical trial. Patients were assigned to either the POCE-assisted management group or the standard management group. Physicians performing POCE examinations received focused training based on the British Society of Echocardiography level 1 standard. The primary outcome was the length of stay in the emergency department (ED), and the secondary outcomes included the time to decision, the time to coronary angiography and diagnostic accuracy of the initial examination. Quality of acquired images was also evaluated. The results revealed that the POCE group had a significantly shorter length of ED stay (209.0 vs. 271.0 min, median difference 64 (31-97) min., p = 0.0003), time to decision (138.0 vs. 252.0 min, p < 0.0001) and time to coronary angiography (29.6 vs. 120.3 h, p = 0.027) than the control group. Furthermore, the error of initial diagnoses was lower in the POCE group (6.3% vs. 30.4%, RR = 0.21 [0.047-0.90]). The implementation of POCE by trained noncardiologists significantly reduced the duration of ED stay and enhanced the management of patients with acute chest pain in the ED. Systematic training enables physicians without prior echocardiography experience to perform POCE accurately and efficiently. Preregistered number of clinical trial: NCT05306730 registered 2022-04-01.

Indexed as

Acute chest painEducationEmergency medicinePoint-of-care echocardiography

Identifiers

PMID41284127

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.