Evidence map›Paper›PMID 41284105›Full record

ArticleMolecular biology reports2025

MPP

Lin-Yu Wang, Yi-Yun Tang, Wei Zou, Ping Zhang, Xiao-Qing Tang, Ping Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lin-Yu Wang *The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, 336 S Dongfeng Road, Hengyang, 421002, Hunan, People's Republic of China.
Yi-Yun Tang *Institute of Neuroscience & Department of Physiology, Hengyang Medical School, University of South China, 28 W Changsheng Road, Hengyang, 421001, Hunan, People's Republic of China.
Wei ZouThe Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, 336 S Dongfeng Road, Hengyang, 421002, Hunan, People's Republic of China.
Ping ZhangThe Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, 336 S Dongfeng Road, Hengyang, 421002, Hunan, People's Republic of China. zhangp415@usc.edu.cn.
Xiao-Qing TangInstitute of Neuroscience & Department of Physiology, Hengyang Medical School, University of South China, 28 W Changsheng Road, Hengyang, 421001, Hunan, People's Republic of China. tangxq-usc@usc.edu.cn.
Ping ZhangThe Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, 336 S Dongfeng Road, Hengyang, 421002, Hunan, People's Republic of China. zhangp-usc@foxmail.com.

Funding

the Clinical Medical Technology Innovation Guidance Project of Hunan Province 2021SK51901the National Natural Science Foundation of China 82271485the Natural Science Foundation of Hunan Province 2023JJ40566
6 · The paper itself

Abstract

backgroundThe microglial (MG) M1/M2 phenotypic switch plays a crucial role in the neuroinflammation of Parkinson's disease (PD), but the underlying mechanism remains unclear. METHODS AND

resultsIn this study, the BV2 microglial cell line was treated with 1 methyl 4 phenyl pyridinium ion (MPP

conclusionsThese results reveal that MPP

Indexed as

1-Methyl-4-phenylpyridiniumMicrogliaSuccinate DehydrogenaseSuccinatesAnimalsCell LineMiceParkinson Disease1-Methyl-4-phenylpyridiniumitaconic acidSuccinate DehydrogenaseSuccinatesIrg1-Itaconate axisMicrogliaMicroglia polarizationParkinson's diseaseSuccinate dehydrogenase

Identifiers

PMID41284105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.