Evidence map›Paper›PMID 41284061›Full record

ReviewSurgery today2026

Adjuvant treatment for esophageal cancer.

Toru Aoyama, Haruhiko Cho, Hideaki Suematsu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Toru Aoyama *Department of Gastric Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan. t-aoyama@lilac.plala.or.jp.
Haruhiko Cho *Department of Gastric Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Hideaki SuematsuDepartment of Gastric Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophagectomy is the standard treatment for resectable esophageal cancer (EC). Recently, the prognosis of EC has gradually improved owing to the introduction of minimally invasive surgery, enhanced postoperative recovery, and perioperative nutritional treatment. However, more than half of the patients who undergo esophagectomy experience recurrence, even after curative esophagectomy. Once EC recurs, the prognosis for patients with recurrent EC is limited. Tumor cell metastasis is the most common cause of recurrence. Micrometastatic cells grow in unresectable regions after curative esophagectomy. Therefore, control of micrometastasis is necessary to prevent the recurrence of EC in the perioperative period. Perioperative adjuvant treatment has been introduced for various malignancies, including EC, to prevent recurrence due to micrometastasis. Since 1990, evidence has emerged regarding postoperative adjuvant treatment, preoperative adjuvant treatment, and perioperative adjuvant treatment for resectable EC. To optimize adjuvant treatment for resectable esophageal cancer, it is necessary to understand the characteristics of each approach before the introduction of adjuvant treatment for resectable esophageal cancer. This review summarizes the background, current status, and future perspectives of adjuvant therapy for resectable esophageal cancer.

Indexed as

Adjuvant treatmentChemotherapyEsophageal cancerRadiation therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.