Evidence map›Paper›PMID 41284057›Full record

ArticleSurgery today2026

Combined use of iPTH and D/W ratio in preoperative diagnosis of parathyroid carcinoma.

Tomohei Matsuo, Akiko Iguchi-Manaka, Aya Sawa, Mai Okazaki, Sachie Hashimoto, Hiroko Bando, Hisato Hara

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tomohei MatsuoDepartment of Breast-Thyroid-Endocrine Surgery, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, 305-8576, Ibaraki, Japan.
Akiko Iguchi-ManakaDepartment of Breast and Endocrine Surgery, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai,, Tsukuba, 305-8575, Ibaraki, Japan. iguchia@md.tsukuba.ac.jp.
Aya SawaDepartment of Breast-Thyroid-Endocrine Surgery, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, 305-8576, Ibaraki, Japan.
Mai OkazakiDepartment of Breast-Thyroid-Endocrine Surgery, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, 305-8576, Ibaraki, Japan.
Sachie HashimotoDepartment of Breast and Endocrine Surgery, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai,, Tsukuba, 305-8575, Ibaraki, Japan.
Hiroko BandoDepartment of Breast and Endocrine Surgery, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai,, Tsukuba, 305-8575, Ibaraki, Japan.
Hisato HaraDepartment of Breast and Endocrine Surgery, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai,, Tsukuba, 305-8575, Ibaraki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeParathyroid carcinoma is an extremely rare malignancy, with an unfavorable clinical outcome and a high recurrence rate after initial surgery. Because surgical removal without tumor cells is the only curative treatment, a preoperative diagnosis is important to develop a strategy for complete removal of tumor cells. This study aimed to examine preoperative methods to differentiate parathyroid carcinoma from parathyroid adenoma.

methodsWe retrospectively analyzed the clinical and pathological features of patients with parathyroid carcinoma or parathyroid adenoma who were undergoing treatment at our hospital between 2011 and 2021.

resultsThe statistical analysis included 7 patients with parathyroid carcinoma and 132 patients with parathyroid adenoma. For the preoperative diagnosis of parathyroid carcinoma, we found that the serum intact parathyroid hormone (iPTH) level was the most useful indicator, showing a significant positive correlation with depth to width (D/W) ratio (r

conclusionThe combination of the serum iPTH level and D/W ratio may be useful in the differential diagnosis of parathyroid carcinoma.

Indexed as

AdenomaBiomarkers, TumorCarcinomaParathyroid HormoneParathyroid NeoplasmsPreoperative CareAdultAgedDiagnosis, DifferentialFemaleHumansMaleMiddle AgedPreoperative PeriodRetrospective StudiesBiomarkers, TumorParathyroid HormoneDepth/width ratioDiagnosisParathyroid carcinomaParathyroid hormone

Identifiers

PMID41284057

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