ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
Optical coherence tomography angiography in evaluating the response of ocular surface squamous neoplasia to topical immunotherapy.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Anterior Segment Optical Coherence Tomography with Angiography for the Cornea and Ocular Surface.Journal of clinical medicine · 2026Review
- Enhanced Imaging of Ocular Surface Lesions.Journal of clinical medicine · 2025Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the changes in OCTA parameters in patients with ocular surface squamous neoplasia (OSSN) during treatment with topical interferon α-2b (IFN-α2b).
methodsThirty-five patients who were diagnosed with OSSN were included in this study. All the patients underwent comprehensive ophthalmic examination, including slit lamp examination, and the size of the lesion was recorded by slit lamp photography. All the patients received topical IFN-α2b (1 million IU/ml, 4 times a day). OCTA images of the ocular surface were obtained at three time points: before initiation of treatment, during treatment, and at tumor resolution. Vessel density (VD), Vessel length density (VLD), and Vessel diameter index (VDI) were measured in superficial and deep vascular flows.
resultsThe mean age of the patients was 60.4 ± 15.7 years. The mean tumor area was 20.7 ± 23.6 mm
conclusionOCTA can be used successfully to evaluate vascular changes in OSSN during medical treatment. Superficial VD and superficial VDI might be useful to evaluate treatment response to topical treatment.
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