Evidence map›Paper›PMID 41283917›Full record

ReviewCell and tissue banking2025

Potential of human amniotic membrane application for articular cartilage regeneration: a review.

Shadi Askari, Elahe Entekhabi, Arezoo Firouzeh, Aylar Eslami Saed, Masoumeh Haghbin Nazarpak

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cell and tissue banking, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shadi Askari *Biomedical Engineering Department, Amirkabir University of Technology, Tehran, Iran.
Elahe Entekhabi *Biomedical Engineering Department, Amirkabir University of Technology, Tehran, Iran.
Arezoo FirouzehBiomedical Engineering Department, Amirkabir University of Technology, Tehran, Iran.
Aylar Eslami SaedBiomedical Engineering Department, Amirkabir University of Technology, Tehran, Iran.
Masoumeh Haghbin NazarpakNew Technologies Research Center (NTRC), Amirkabir University of Technology, 424 Hafez Ave., P.O Box 15875-4413, Tehran, Iran. haghbin@aut.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regeneration of articular cartilage disorders is one of the critical challenges in musculoskeletal medicine. Tissue engineering could represent a therapeutic option to support cartilage regeneration. Natural and biological materials are appropriate for fabricating tissue engineering scaffolds because of their similarity to natural tissues. The properties of amniotic membranes, including low immunogenicity, anti-inflammatory role, cell loading capability, expression of various growth factors, and chondroprotective effect, make them an interesting option for cartilage regeneration. This review studied the structure of articular cartilage and potential applications of the human amniotic membrane (AM) for articular cartilage regeneration. In addition, processing and decellularization methods of AM and the most common forms of amniotic membrane used in cartilage regeneration, including sheet, injectable form, and 3D forms, were studied. This review highlights the benefits of amniotic membrane applications in cartilage regeneration and clinical trial studies.

Indexed as

AmnionCartilage, ArticularRegenerationTissue EngineeringAnimalsHumansTissue ScaffoldsArticular cartilageDecellularizationHuman amniotic membraneOsteoarthritisRegenerationTissue engineering

Identifiers

PMID41283917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.