Evidence map›Paper›PMID 41283679›Full record

ArticlemSystems2025

Spatiotemporal development of late and moderate preterm infant gut and oral microbiomes and impact of gestational age on early colonization.

Sinéad Ahearn-Ford, Andreas Kakaroukas, Gregory R Young, Andrew Nelson, Marieke Abrahamse-Berkeveld, Ruurd M van Elburg, Darren Smith, Janet E Berrington, Nicholas D Embleton, Christopher J Stewart

Abstract read
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sinéad Ahearn-FordTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Andreas KakaroukasNewcastle Neonatal Service, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals National Health Service (NHS) Foundation Trust, Newcastle upon Tyne, United Kingdom.
Gregory R YoungTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Andrew NelsonDepartment of Applied Science, Northumbria University, Newcastle upon Tyne, United Kingdom.
Marieke Abrahamse-BerkeveldDanone Nutricia Research, Utrecht, the Netherlands.
Ruurd M van ElburgEmma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
Darren SmithDepartment of Applied Science, Northumbria University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-4925-467X
Janet E BerringtonTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Nicholas D EmbletonNewcastle Neonatal Service, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals National Health Service (NHS) Foundation Trust, Newcastle upon Tyne, United Kingdom.
Christopher J StewartTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-6033-338X

Funding

Danone Early Life Nutrition NA
6 · The paper itself

Abstract

Microbiome research focusing on late and moderate preterm infants (LMPT; 32 to 36 weeks gestation) is limited, despite rising LMPT births, large healthcare burdens, and increased risks of multiple morbidities, potentially microbially related. In this longitudinal cohort study, 16S rRNA gene sequencing was used to analyze 371 stool and 402 saliva samples from 160 LMPT infants, collected at five time points between birth and 12 months corrected age (CA), to describe spatial and temporal variability in gut and oral microbiomes. Paired stool and saliva samples (

Indexed as

Gastrointestinal MicrobiomeGestational AgeInfant, PrematureMouthBacteriaFecesFemaleHumansInfantInfant, NewbornLongitudinal StudiesMaleRNA, Ribosomal, 16SSalivaRNA, Ribosomal, 16Sgut microbiomeoral microbiomepreterm infantspatiotemporal microbiome development

Identifiers

PMID41283679
PMCPMC12710329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.