Evidence map›Paper›PMID 41283561›Full record

ReviewJournal of functional morphology and kinesiology2025

Knee Health Is a Major Determinant of Mobility Across the Healthspan.

Brandon Marshall Peoples, Kenneth D Harrison, Michael A Samaan, Christopher B Mobley, David T Redden, Jaimie A Roper

Abstract readReview
In one paragraph

Review in Journal of functional morphology and kinesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brandon Marshall PeoplesSchool of Kinesiology, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-2960-9042
Kenneth D HarrisonSchool of Kinesiology, Auburn University, Auburn, AL 36849, USA.
Michael A SamaanDepartment of Kinesiology & Health Promotion, University of Kentucky, Lexington, KY 40506, USA.ORCID 0000-0003-0597-1159
Christopher B MobleySchool of Kinesiology, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-4045-9962
David T ReddenEdward Via College of Osteopathic Medicine, Auburn University, Auburn, AL 36849, USA.
Jaimie A RoperSchool of Kinesiology, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-8760-8881

Funding

CTSA Predoctoral T32 at the University of Alabama at BirminghamT32TR004767 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jennifer S Pollock · 2024 to 2026
$1.7M
Quantifying the Mechanism and Impact of Hip Extensor Muscle Dysfunction During Aerobic Exercise in Hip OsteoarthritisK01AG073698 · NIA · UNIVERSITY OF KENTUCKY · PI Michael A Samaan · 2022 to 2026
$612k
NCATS NIH HHS T32 TR004767NIA NIH HHS K01 AG073698
6 · The paper itself

Abstract

Knee health constitutes a pivotal determinant of locomotor function and overall mobility throughout the healthspan. Impairments in knee function lead to a series of biomechanical and physiological alterations that pose substantial public health challenges and economic burdens worldwide. This review synthesizes evidence that delineates the complex and multifaceted relationship between knee health and mobility, emphasizing the interplay across various domains in adult populations. Knee health is conceptualized as a dynamic, interconnected system whereby structural integrity, neuromuscular mechanisms, biomechanical adaptations, and functional mobility are intricately interrelated through cascades of mechanistic processes operating across different temporal stages. A comprehensive understanding of these interrelationships is necessary for developing precise and targeted interventions that aim to preserve mobility and functional independence throughout the healthspan.

Indexed as

ACLgait biomechanicsknee injurymobilityosteoarthritis

Identifiers

PMID41283561
PMCPMC12641873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.