Evidence map›Paper›PMID 41283432›Full record

ReviewJournal of xenobiotics2025

A Systematic Review: Migration of Chemical Compounds from Plastic Material Containers in Food and Pharmaceutical Fields.

Laura Culleré, Estela Sangüesa, Laura Lomba, María Pilar Ribate, Estefanía Zuriaga, Cristina B García

Abstract readReview
In one paragraph

Review in Journal of xenobiotics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura CulleréFacultad de Ciencias de la Salud, Universidad San Jorge, Campus Universitario, Autov. A23 Km 299, Villanueva de Gállego, 50830 Zaragoza, Spain.ORCID 0000-0001-7295-4573
Estela SangüesaFacultad de Ciencias de la Salud, Universidad San Jorge, Campus Universitario, Autov. A23 Km 299, Villanueva de Gállego, 50830 Zaragoza, Spain.ORCID 0000-0002-3818-4488
Laura LombaFacultad de Ciencias de la Salud, Universidad San Jorge, Campus Universitario, Autov. A23 Km 299, Villanueva de Gállego, 50830 Zaragoza, Spain.ORCID 0000-0002-7091-8138
María Pilar RibateFacultad de Ciencias de la Salud, Universidad San Jorge, Campus Universitario, Autov. A23 Km 299, Villanueva de Gállego, 50830 Zaragoza, Spain.ORCID 0000-0002-1466-0179
Estefanía ZuriagaFacultad de Ciencias de la Salud, Universidad San Jorge, Campus Universitario, Autov. A23 Km 299, Villanueva de Gállego, 50830 Zaragoza, Spain.ORCID 0000-0001-6054-7313
Cristina B GarcíaFacultad de Ciencias de la Salud, Universidad San Jorge, Campus Universitario, Autov. A23 Km 299, Villanueva de Gállego, 50830 Zaragoza, Spain.ORCID 0000-0002-9036-3483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A systematic review was conducted on the migration of compounds from plastic containers in the food and pharmaceutical industries, using Web of Science databases and following PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). The protocol has been registered with the OSF registry, with the DOI 10.17605/OSF.10/UQ3T2. This review included only review articles in English published within the last fifteen years. Four reviewers independently screened titles and abstracts, discussing inclusion criteria. In this comprehensive evaluation of the information present in an Excel spreadsheet, a substantial number of records were discarded because they were not representative of the topic under study. Following the review process, a total of twenty-eight key records were selected, primarily focusing on migration in the food and pharmaceutical sectors. Of these, twenty-four addressed only food, just two addressed only pharmaceutical sector, and two covered both fields, highlighting limited information on migration in pharmaceuticals, cosmetics, and related products. The analysis emphasized the types of compounds studied, the analytical methods employed, the migration tests conducted, and the toxicity assessments undertaken. The most frequently assessed compounds included phthalates, endocrine disruptors like bisphenol A, and non-intentionally added substances (NIAS). Analytical methods used typically involved pre-treatment steps, such as liquid-liquid or solid-phase extraction, followed by gas or liquid chromatography, depending on compound volatility.

Indexed as

chemical compoundsdrugsendocrine disruptorsfoodleachingmigrationNIASpharmaceuticalphthalatesplastic containers

Identifiers

PMID41283432
PMCPMC12641956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.