Evidence map›Paper›PMID 41283328›Full record

ArticleNon-coding RNA2025

Exploring microRNAs, One Cell at a Time.

Jessica Kreutz, Tijana Mitić, Andrea Caporali

Abstract read
In one paragraph

Article in Non-coding RNA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jessica KreutzCentre for Cardiovascular Science, The Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.ORCID 0009-0000-9386-8121
Tijana MitićCentre for Cardiovascular Science, The Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
Andrea CaporaliCentre for Cardiovascular Science, The Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.ORCID 0000-0003-2905-3096

Funding

British Heart Foundation PG/22/10916
6 · The paper itself

Abstract

The emergence of single-cell sequencing and computational analysis has dramatically improved our understanding of cellular diversity and gene expression dynamics. The rapid advancement of high-throughput omics technologies has led to an exponential growth in biological data. However, many gene regulatory processes at the single-cell level remain underexplored, especially those regulated by post-transcriptional mechanisms involving microRNAs (miRNAs). miRNAs are essential regulators of gene expression, affecting cellular functions in both normal and disease states. Recent innovations, such as single-cell gene expression profiling and bioinformatic analysis, have enabled comprehensive studies that uncover previously hidden miRNA profiles. In this context, we present experimental tools and computational methods for analysing cell-specific miRNA abundance and investigating their mechanisms. These approaches are expected to reveal the complex nature of miRNA biology and, more broadly, enhance our understanding of life sciences and diseases.

Indexed as

bioinformaticsmicroRNAsingle-cell sequencingspatial transcriptomics

Identifiers

PMID41283328
PMCPMC12641660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.