ArticleEpidemiologia (Basel, Switzerland)2025
Educational Level Mediates the Relationship Between Knowledge and Preventive Practices in Multidrug-Resistant Tuberculosis Patients.
Article in Epidemiologia (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundMultidrug-resistant tuberculosis (MDR-TB) prevention presents significant challenges in Peruvian healthcare settings, with substantial gaps in knowledge implementation and preventive practices. However, little is known about how patients' sociodemographic factors influence the translation of knowledge into preventive practices.
methodsThis cross-sectional study examined the associations between knowledge, preventive practices, and potential mediating roles of occupation, educational level, and sex among MDR-TB patients. We surveyed 280 patients from twelve health centers in the Piura-Castilla Network, Peru, recruited from urban (38.55%), marginal urban (32.06%), and rural (29.39%) areas through nonprobability convenience sampling. Participants represented diverse occupational backgrounds, including housewives (19.85%), workers (20.99%), and unemployed individuals (23.28%).
resultsMeasurement instruments were validated through confirmatory factor analysis, demonstrating adequate reliability (McDonald's ω > 0.80) and discriminant validity (HTMT < 0.85). Path analysis using structural equation modeling assessed direct and indirect relationships. Knowledge showed a significant direct association with preventive practices (β = 0.194,
conclusionsEducational level appears to facilitate the translation of knowledge into preventive practices among MDR-TB patients, though the cross-sectional design precludes causal or directional inferences. Healthcare institutions should develop tailored educational interventions according to patients' educational backgrounds, including literacy-sensitive materials, simplified visual aids, and personalized counseling sessions to enhance MDR-TB prevention effectiveness in clinical settings.
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