ArticleEpidemiologia (Basel, Switzerland)2025
Recreational Nitrous Oxide Use and Associated Neuropsychiatric Presentations in Patients Attending the Emergency Department.
Article in Epidemiologia (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesNitrous oxide (N
methodsWe conducted a retrospective observational review of EMH referrals between August 2020 and July 2024. Inclusion criteria were patients with documented recreational N
resultsOf 25 identified patients, 23 met inclusion criteria (12 males, 11 females; mean age 29.3 ± 8.3 years). Psychotic symptoms were reported in 11/23 (47.8%, 95% CI 27.3-69.0) and suicidal ideation or self-harm in 8/23 (34.8%, 95% CI 17.2-55.7). Neurological symptoms, including paraesthesia and ataxia, occurred in 5/23 (21.7%, 95% CI 7.5-43.7). Concurrent substance use was documented in 19/23 (82.6%, 95% CI 61.2-95.0), most frequently cannabis, alcohol, and tobacco. Over half of patients (12/23; 52.2%, 95% CI 30.6-73.2) identified as culturally and linguistically diverse (CALD).
conclusionsAmong EMH-referred ED patients, recreational N
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