Evidence map›Paper›PMID 41283252›Full record

ArticleMedical sciences (Basel, Switzerland)2025

Temporal Trends in Cardiovascular Health Metrics in Italy, 2015-2024: A Ten-Year Report from the Longevity Check-Up (Lookup) 8+ Study.

Stefano Cacciatore, Elena Levati, Riccardo Calvani, Matteo Tosato, Francesca Ciciarello, Vincenzo Galluzzo, Sara Salini, Andrea Russo, Emanuele Marzetti, Francesco Landi and 1 more

Abstract read
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stefano CacciatoreDepartment of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.ORCID 0000-0001-7504-3775
Elena LevatiDepartment of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.
Riccardo CalvaniDepartment of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.ORCID 0000-0001-5472-2365
Matteo TosatoFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Largo Agostino Gemelli 8, 00168 Rome, Italy.ORCID 0000-0001-5750-9746
Francesca CiciarelloFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Largo Agostino Gemelli 8, 00168 Rome, Italy.ORCID 0000-0002-9021-9182
Vincenzo GalluzzoFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Largo Agostino Gemelli 8, 00168 Rome, Italy.ORCID 0000-0003-4620-5979
Sara SaliniFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Largo Agostino Gemelli 8, 00168 Rome, Italy.ORCID 0000-0002-9093-4776
Andrea RussoFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Largo Agostino Gemelli 8, 00168 Rome, Italy.ORCID 0000-0003-2475-0925
Emanuele MarzettiDepartment of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.ORCID 0000-0001-9567-6983
Francesco LandiDepartment of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.
Lookup 8+ Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe objective of this ten-year report is to describe temporal trends in the cardiovascular health (CVH) score and its individual components across ages and sexes. We also examined the impact of the post-COVID-19 period on ideal CVH and identified demographic predictors of favorable cardiovascular risk profiles.

methodsData for this cross-sectional study were collected between 2015 and 2024 as part of the Lookup 8+ project, an ongoing initiative integrating field-based CVH assessments across Italy. CVH was operationalized using a modified CVH score (0-7 points) inspired by Life's Simple 7, combining behavioral and clinical metrics. Trends over time and across demographic groups were examined using descriptive statistics and multivariable models adjusted for age, sex, and year of assessment.

resultsThe study included 18,491 participants (mean age 56.1 ± 14.8 years; 55.2% women). After an initial decline in CVH score between 2015 and 2017 (mean score from 4.39 to 3.95), a gradual improvement followed, reaching 4.41 in 2024. Younger adults (18-39 years; 71.9% in 2024) and women (56.8%) consistently showed the highest prevalence of ideal CVH (score ≥ 5). The post-COVID-19 period was independently associated with higher odds of ideal CVH (OR 1.32; 95% CI 1.24-1.40). While blood pressure and cholesterol metrics improved, dietary quality and glycemic control worsened over time.

conclusionsFrom 2015 to 2024, overall CVH improved among Lookup participants, particularly among younger individuals after the COVID-19 pandemic. However, substantial age- and sex-related gaps remain, requiring targeted and equity-oriented prevention efforts.

Indexed as

Cardiovascular DiseasesCOVID-19LongevityAdolescentAdultAgedCross-Sectional StudiesFemaleHeart Disease Risk FactorsHumansItalyMaleMiddle AgedSARS-CoV-2Young Adultcardiovascular healthCOVID-19 pandemichealth behaviorhealth surveysLife’s Simple 7primary preventionpublic health surveillancerisk factors

Identifiers

PMID41283252
PMCPMC12641886

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.