Evidence map›Paper›PMID 41283175›Full record

ArticleWorld journal of clinical cases2025

Endogenous modulators in lung cancer.

Namra Patel, Viral Patel, Salim Surani

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Namra PatelDepartment of Medicine, GMERS College and Hospital, Valsad 396001, Gujarāt, India.
Viral PatelDepartment of Internal Medicine, Baptist Hospital of Southeast Texas, Beaumont, TX 77701, United States.
Salim SuraniDepartment of Medicine and Pharmacology, Texas A&M University, College Station, TX 77843, United Statessrsurani@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This editorial aimed to consolidate current evidence on the role of major endogenous modulators-nitric oxide (NO), prostaglandins (PGs), thromboxanes (TXs), and endothelins (ETs) in the lung carcinogenesis, their receptor-specific actions, compensatory feedback mechanisms, and their role in tumor immune evasion and angiogenesis. We searched PubMed and Google Scholar with free-text and MeSH combinations of terms including "lung cancer", "nitric oxide", "inducible NOS", "COX-2", "prostaglandin E

Indexed as

AngiogenesisBiomarkersCyclooxygenaseLung cancerNitric oxideProstaglandinsThromboxanesTumor microenvironment

Identifiers

PMID41283175
PMCPMC12635841

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.