Evidence map›Paper›PMID 41283172›Full record

ArticleTherapeutic advances in gastroenterology2025

A positive

Geethanjali Rajagopal, Raghavendra Paknikar, Zifeng Deng, Sujaata Dwadasi, Donald V Goens, Maryam Zafer, Russell D Cohen, Atsushi Sakuraba, David T Rubin, Sushila Dalal and 2 more

Abstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Geethanjali RajagopalDepartment of Internal Medicine, University of Chicago Medicine, 5841 S. Maryland Avenue, Suite MC7082, Chicago, IL 60637, USA.ORCID https://orcid.org/0009-0001-2417-1440
Raghavendra PaknikarSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Zifeng DengSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Sujaata DwadasiSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Donald V GoensSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Maryam ZaferSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Russell D CohenSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Atsushi SakurabaSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
David T RubinSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Sushila DalalSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Dejan MicicSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.
Joel PekowSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Objectives: To assess the clinical outcomes of hospitalized ASUC patients with CDI. Design: Retrospective, single-center study. Methods: Medical records of ASUC patients admitted from December 1, 2008, to June 1, 2018, were reviewed. Primary outcomes included hospital duration, in-hospital colectomy rates, and escalation of immunosuppression at discharge. Secondary outcomes included readmission rates and use of salvage therapy. Results: Among 410 ASUC patients, 67 tested positive for CDI. No significant differences in hospital duration, colectomy rates, or readmission rates were found between CDI-positive and CDI-negative groups. CDI-positive patients were less likely to receive intravenous corticosteroids. Conclusion: A positive CDI test in ASUC patients does not correlate with worse clinical outcomes. Based on these results, CDI should be ruled out and treated in hospitalized patients with severe ulcerative colitis without delaying ASUC management.

Indexed as

acute severe ulcerative colitisClostridioides difficile

Identifiers

PMID41283172
PMCPMC12639233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.