Evidence map›Paper›PMID 41283093›Full record

ArticleIndian journal of surgical oncology2025

Role of Portal Vein Embolization Alone in Surgical Management of Locally Advanced Gall Bladder Cancer (PROVE-GBC): A Prospective Clinical Trial.

Nihar Ranjan Dash, Vedavyas Mohapatra, Kumble Seetharaman Madhusudan, Sujoy Pal, Lokesh Agarwal

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Article in Indian journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nihar Ranjan DashDepartment of Gastrointestinal Surgery and Liver Transplant, All India Institute of Medical Sciences, New Delhi, India.
Vedavyas MohapatraDepartment of Surgical Gastroenterology, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, India.
Kumble Seetharaman MadhusudanDepartment of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India.
Sujoy PalDepartment of Gastrointestinal Surgery and Liver Transplant, All India Institute of Medical Sciences, New Delhi, India.
Lokesh AgarwalDepartment of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342001 India.ORCID 0000-0002-7731-3908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curative resections are the cornerstone in the management of patients with resectable locally advanced gallbladder cancer (LAGBC). Portal vein embolization (PVE) is a frequently used approach for future liver remnant (FLR) hypertrophy prior to extended hepatectomies. This study was conducted to assess the clinical utility of PVE in patients with LAGBC requiring major hepatectomy. This prospective study included all patients of LAGBC requiring major liver resection who underwent PVE from August 2015 to July 2021. The technical and clinical success rates and the peri-procedural complications of PVE and hypertrophy of FLR after PVE were evaluated along with the assessment and comparison of survival rates in patients with and without definitive surgery. Thirty-five patients (mean age 46.1 years; 18 males) of LAGBC were included in the study. The technical success of PVE was 100%. Post-PVE imaging was performed for 28 patients, of whom 10 had progressive disease. Only 18 patients showed surgically resectable disease on post-PVE imaging. The median percentage of FLR volume increased from 19.6 to 26.2% after PVE (

Indexed as

Carcinoma gallbladderExtended hepatectomyExtended right hepatectomyHepatectomyJaundiceLocally advanced gallbladder cancerPortal vein embolization

Identifiers

PMID41283093
PMCPMC12630502

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.