Evidence map›Paper›PMID 41283084›Full record

ReviewIndian journal of surgical oncology2025

Decoding the Genetic Landscape of Postoperative Nausea and Vomiting in Cancer Surgery: A New Frontier in Personalized Medicine Driven by Genome-Wide Association Studies.

Mehdi Khosravi-Mashizi, Mohammad Hossein Antikchi, Mohammad Mehdi Atarod, Nima Narimani, Hossein Golestanpour, Amirhosein Naseri, Ahmad Shirinzadeh-Dastgiri, Seyed Masoud HaghighiKian, Mahsa Danaei, Seyed Alireza Dastgheib and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Indian journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mehdi Khosravi-MashiziDepartment of General Surgery, Hazrat-e Rasool General Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mohammad Hossein AntikchiDepartment of Internal Medicine, Yazd Branch, Islamic Azad University, Yazd, Iran.
Mohammad Mehdi AtarodDepartment of Urology, Hasheminejad Kidney Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Nima NarimaniDepartment of Urology, Hasheminejad Kidney Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Hossein GolestanpourDepartment of Genetics, Marvdasht Branch, Azad University, Marvdasht, Iran.
Amirhosein NaseriDepartment of Colorectal Surgery, Imam Reza Hospital, AJA University of Medical Sciences, Tehran, Iran.
Ahmad Shirinzadeh-DastgiriDepartment of Surgery, School of Medicine, Shohadaye Haft-e Tir Hospital, Iran University of Medical Sciences, Tehran, Iran.
Seyed Masoud HaghighiKianDepartment of General Surgery, Hazrat-e Rasool General Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mahsa DanaeiDepartment of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Seyed Alireza DastgheibDepartment of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Maryam YeganegiDepartment of Obstetrics and Gynecology, School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran.
Amirhossein RahmaniDepartment of Plastic Surgery, School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran.
Hossein NeamatzadehMother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative nausea and vomiting (PONV) is a common complication following surgery, especially among cancer patients. It affects comfort, extends hospital stays, and increases healthcare costs. Advances in genomic research present an opportunity to explore genetic predispositions to PONV, potentially enabling targeted interventions and improved management strategies. This review consolidates findings from genome-wide association studies (GWAS) to identify genetic links to PONV in cancer patients and evaluate their implications for personalized medicine. A thorough search of databases such as PubMed, Scopus, and Web of Science identified GWAS studies on genetic predispositions to PONV in cancer surgery patients up to August 25, 2024. Studies were selected based on inclusion criteria that required reporting genetic associations with PONV, and the findings were analyzed for commonalities and discrepancies. Significant

Indexed as

Cancer surgeryGenetic factorsGenome-wide association studiesPersonalized medicinePolymorphismsPostoperative nausea and vomiting

Identifiers

PMID41283084
PMCPMC12630498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.