Evidence map›Paper›PMID 41283025›Full record

ArticleFrontiers in public health2025

Hydration and health at ages 40-70 years in Salzburg Austria is associated with a median total water intake over 40 mL/kg including at least 1 L/d plain drinking water.

Jodi D Stookey, Patrick B Langthaler, Thomas K Felder, Vanessa N Frey, Antje van der Zee-Neuen, Karin Schindler, Ludmilla Kedenko, Bernhard Iglseder, Eugen Trinka, Florian Lang and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07464002 (Studie Zum Habituellen Durst Und Adapt Durst Studie), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07464002 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Studie Zum Habituellen Durst Und Adapt Durst Studie: Habitual Thirst Study and Adapt Thirst Study

TypeinterventionalSponsorJodi StookeyRan2026 to 2027Enrolled120ConditionsChronic Underhydration, Thirst, Due to Deprivation of Water, Aestivation MetabolismArmsDrinking water to dilute urine
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jodi D StookeyWater & Hydration Translational Epidemiological Research (WAHTER) LLC, San Francisco, CA, United States.
Patrick B LangthalerDepartment of Neurology, Christian Doppler University Hospital, Paracelsus Medical University and Centre for Cognitive Neuroscience, Member of the European Reference Network EpiCARE, Salzburg, Austria.
Thomas K FelderDepartment of Laboratory Medicine, Paracelsus Medical University, Salzburg, Austria.
Vanessa N FreyDepartment of Neurology, Christian Doppler University Hospital, Paracelsus Medical University and Centre for Cognitive Neuroscience, Member of the European Reference Network EpiCARE, Salzburg, Austria.
Antje van der Zee-NeuenCenter for Physiology, Pathophysiology and Biophysics, Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria.
Karin SchindlerDivision of Endocrinology and Metabolism, Medical University Vienna, Vienna, Austria.
Ludmilla KedenkoDepartment of Internal Medicine I, St. Johanns University Hospital, Paracelsus Medical University, Salzburg, Austria.
Bernhard IglsederDepartment of Geriatrics, Christian Doppler University Hospital, Paracelsus Medical University, Salzburg, Austria.
Eugen TrinkaDepartment of Neurology, Christian Doppler University Hospital, Paracelsus Medical University and Centre for Cognitive Neuroscience, Member of the European Reference Network EpiCARE, Salzburg, Austria.
Florian LangDepartment of Physiology, Eberhard Karls University, Tuebingen, Germany.
Dieter HäussingerClinic for Gastroenterology, Hepatology, and Infectious Diseases, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Markus RitterCenter for Physiology, Pathophysiology and Biophysics, Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria.
Bernhard PaulweberDepartment of Internal Medicine I, St. Johanns University Hospital, Paracelsus Medical University, Salzburg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: To address longstanding questions about how much plain water to drink for hydration and long-term health, this study described the plain water intake (PWI) of people without chronic health conditions (CHC), at ages 40-70 years, who met hydration criteria (Healthy+Hydrated). Methods: Community-dwelling participants in the population-based Paracelsus 10,000 study in Salzburg, Austria ( Results: For Healthy+Hydrated women, the median PWI and TWI were 1.5 L/d (22 mL/kg) and 2.9 L/d (45 mL/kg), respectively. For Healthy+Hydrated men, the median PWI and TWI were 1.3 L/d (17 mL/kg) and 3.0 L/d (40 mL/kg). None of the Healthy+Hydrated reported zero PWI. In gender-specific Poisson models, the Healthy+Hydrated group had significantly lower relative risk of PWI < 20 mL/kg AND TWI < 45 mL/kg than each of the CHC+Hydrated, Healthy+Not Hydrated, and CHC+Not Hydrated groups. For Healthy+Hydrated participants with >60% of TWI from PWI, PWI ranged between 20 and 45 mL/kg/d. Conclusion: In the Paracelsus 10,000 study population, hydration and health at ages 40-70 years was associated with a median PWI of at least 1 L/d.

Indexed as

DehydrationDrinkingDrinking WaterHealth StatusAdultAgedAustriaCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesDrinking Wateradequate intakeAustriadrinking waterhydrationwater intake

Identifiers

PMID41283025
PMCPMC12634361

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.