Evidence map›Paper›PMID 41282993›Full record

ReviewPeerJ2025

AIMP1: multifunctional regulator in physiology and pathology with therapeutic implications.

Xunan Yuan, Xinmiao Wang, Xiaodan Ma, Yaping Mao, Qinqin Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xunan Yuan *Research Institute of Mental Health, Jining Medical University, Jining, Shandong Province, China.
Xinmiao Wang *Research Institute of Mental Health, Jining Medical University, Jining, Shandong Province, China.
Xiaodan MaResearch Institute of Mental Health, Jining Medical University, Jining, Shandong Province, China.
Yaping MaoSchool of Public Health, Shenyang Medical College, Shenyang, Liaoning Province, China.
Qinqin WangResearch Institute of Mental Health, Jining Medical University, Jining, Shandong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 (AIMP1), also referred to as p43, serves as an auxiliary factor of the macromolecular aminoacyl tRNA synthetase complex. Beyond its classical role in the assembling the multisynthetase complex (MSC) for protein translation, growing evidence has elucidated that AIMP1 plays a pivotal role in regulating immune response, brain function and angiogenesis. Furthermore, accumulating studies have demonstrated that AIMP1 is involved in a spectrum of pathological processes, including cancer, immunity associated disorders, and neurological diseases. Herein, we summarize the current research regarding the functions of AIMP1 under both physiological and pathological conditions, with a particular focus on its therapeutic potential in these diseases.

Indexed as

NeoplasmsRNA-Binding ProteinsAnimalsBrainHumansNervous System DiseasesRNA-Binding ProteinsAIMP1CancerImmunity associated disordersNeurological diseases

Identifiers

PMID41282993
PMCPMC12637037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.