In one paragraphArticle in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Jessica S JohnsonDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-4519-3120 Chaoyu LiuDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Judit García-GonzálezDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-6245-740X Shing Wan ChoiDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-2215-3238 Eating Disorders Working Group of the Psychiatric Genomics Consortium (PGC-ED)
Cynthia M BulikDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0001-7772-3264 Paul F O'ReillyDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-7515-0845 Funding
Research Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Mary Sano · 2020 to 2026
$31.0MEating Disorders Genetics Initiative (EDGI)R01MH120170 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M · 2019 to 2023
$7.2MHigher Order Chromatin and Genetic Risk for SchizophreniaR01MH106056 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI AKBARIAN, SCHAHRAM, BRENNAND, KRISTEN JENNIFER · 2015 to 2023
$6.7M1/3 Eating Disorders Genetics Initiative 2 (EDGI2)R01MH136149 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CYNTHIA M BULIK, Laura Marianne Huckins · 2024 to 2026
$5.1MModeling the interaction of physiological and environmental stressors on common variants to psychiatric traitsR01ES033630 · NIEHS · YALE UNIVERSITY · PI Kristen Jennifer Brennand · 2022 to 2026
$4.6MFunctional convergence following disruption of diverse genes associated with neurodevelopmental disordersR01MH123155 · NIMH · YALE UNIVERSITY · PI BRENNAND, KRISTEN JENNIFER, RUDERFER, DOUGLAS · 2021 to 2025
$4.1M1/7 PGC: Advancing Discovery and ImpactR01MH124871 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, SULLIVAN, PATRICK F · 2021 to 2025
$3.5MNext-generation, pathway-specific, polygenic risk scoresR01MH122866 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI O'REILLY, PAUL FRANCIS · 2020 to 2024
$3.1MIntegrated Multiscale Networks in SchizophreniaR01MH109897 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRENNAND, KRISTEN JENNIFER, ROUSSOS, PANAGIOTIS · 2016 to 2020
$3.0MBridgePRS: bridging the gap in polygenic risk scores between ancestries.R01HG012773 · NHGRI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Paul Francis O'Reilly · 2023 to 2026
$2.6MBig Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M3/7 Psychiatric Genomics Consortium: Advancing Discovery and ImpactR01MH124839 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ANDREASSEN, OLE A, HUCKINS, LAURA MARIANNE · 2021 to 2025
$2.0MNHGRI NIH HHS K99 HG013547NHGRI NIH HHS R01 HG012773NIA NIH HHS P30 AG066514NIEHS NIH HHS R01 ES033630NIH HHS S10 OD018522NIH HHS S10 OD026880NIMH NIH HHS R01 MH106056NIMH NIH HHS R01 MH109897NIMH NIH HHS R01 MH120170NIMH NIH HHS R01 MH122866NIMH NIH HHS R01 MH123155NIMH NIH HHS R01 MH124839NIMH NIH HHS R01 MH124871NIMH NIH HHS R01 MH134039NIMH NIH HHS R01 MH136149NIMH NIH HHS R56 MH101454NIMH NIH HHS R56 MH129437
6 · The paper itselfAbstract
Genome-wide association studies of common disorders reveal polygenic architectures. While these variants may converge into biologically relevant pathways, how polygenicity aggregates across pathways remains unknown. We studied polygenicity at the pathway level in anorexia nervosa (AN)-a psychiatric disorder with multi-systemic clinical manifestations. We constructed pathway-based polygenic risk scores (pathway PRS) to model genetic risk at the pathway level for 3,687 individuals with AN and 11,257 controls. We identified 497 AN-associated pathways after Bonferroni correction, including pathways involved in the brain, metabolism, immunity/stress, and reproduction/development. A strong positive correlation was observed between number of pathways ranking at top 10% and AN case proportion (
Identifiers
PMID41282944
PMCPMC12632654
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