Evidence map›Paper›PMID 41282941›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Analyzing Information Disparities across Modalities in Mortality Prediction.

Chanhwi Kim, WonJin Yoon, Hoonick Lee, Jung-Oh Lee, Majid Afshar, Jaewoo Kang, Timothy Miller

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chanhwi KimDept. of Computer Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
WonJin YoonDept. of Pediatrics, Harvard Medical School, Boston, MA 10587, USA.ORCID 0000-0002-6435-548X
Hoonick LeeDept. of Computer Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.ORCID 0009-0003-5752-813X
Jung-Oh LeeDept. of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Majid AfsharDept. of Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-6368-4652
Jaewoo KangDept. of Computer Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.ORCID 0000-0001-6798-9106
Timothy MillerDept. of Pediatrics, Harvard Medical School, Boston, MA 10587, USA.ORCID 0000-0003-4513-403X

Funding

Extended Methods and Software Development for Health NLPR01GM114355 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BETHARD, STEVEN, SAVOVA, GUERGANA K. · 2016 to 2024
$5.0M
Learning Universal Patient Representations with Hierarchical TransformersR01LM012973 · NLM · BOSTON CHILDREN'S HOSPITAL · PI Timothy A Miller · 2019 to 2026
$3.5M
NIGMS NIH HHS R01 GM114355NLM NIH HHS R01 LM012973
6 · The paper itself

Abstract

Recent advances in deep learning have enabled the integration of heterogeneous data modalities for clinical prediction, allowing models to exploit complex information embedded within electronic health records (EHRs). Among these modalities, chest radiographs (CXRs) provide a rich source of visual information that can enhance patient outcome prediction for patients in the intensive care unit (ICU). However, the comparative impact of different CXR representations-raw images versus radiology reports-on predictive performance has not been systematically investigated. Such comparisons are essential for identifying the most informative modality and understanding how it complements other data sources. This study compares the predictive utility of raw CXRs versus radiology reports for 30-day post-discharge mortality prediction in ICU patients. We employed a Vision-Language Model (VLM) with patient discharge notes. On a filtered subset of the MIMIC-IV dataset (n = 1,360), augmenting discharge notes with CXRs achieved the best performance (AUROC = 0.843), surpassing both the discharge-note-only (AUROC = 0.816) and radiology-report-augmented (AUROC = 0.804) models. The experiments demonstrated that combining raw CXRs with discharge notes consistently outperformed models augmented with radiology reports. A radiologist's review further revealed that reports often omitted clinically relevant findings visible in the images, highlighting that CXRs convey richer prognostic signals for mortality risk. These findings underscore the critical role of modality selection in clinical AI systems and suggest that textual summaries should be used as surrogates for multimodal data with caution, as they may fail to capture critical predictive information.

Indexed as

Chest RadiographsElectronic Health RecordsMultimodal LearningPost-discharge MortalityVision–Language Models

Identifiers

PMID41282941
PMCPMC12636669

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.