ArticlemedRxiv : the preprint server for health sciences2025
Characterizing social behavior relevant for tuberculosis transmission in four low- and middle-income countries.
Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Tuberculosis (TB) is caused by Methods: We use data from the GlobalMix study, which characterized social behavior across four countries, to evaluate differences in age-sex patterning and locations of contact across four moderate- to high-TB burden countries. Healthy individuals self-completed a survey about their daily person-to-person interactions and locations in which they spent time. To capture the Results: The most prominent shifts in the profile of exposure occur at entry to primary school (5-9 years) and early adulthood (20-29 years). Community locations varied in their relative importance as locations of transmission by country and age group, with school most important in India and Guatemala, transit more important in Pakistan, and others' homes most important in Mozambique. Conclusions: Our findings demonstrate that locations of community transmission are likely varied across settings, underscoring the importance of interventions designed specifically for the communities in which they will be implemented.
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