Evidence map›Paper›PMID 41282729›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Estimating the sensitivity of non-treponemal and treponemal antibody tests in primary syphilis.

Stephanie F Sweitzer, Jane S Chen, Mitch M Matoga, Ligang Yang, Eduardo Lopez-Medina, Jonny A Garcia-Luna, Irving F Hoffman, Bin Yang, Juan C Salazar, Justin D Radolf and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Stephanie F SweitzerDivision of Infectious Diseases, Department of Internal Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Jane S ChenDivision of Infectious Diseases, Department of Internal Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Mitch M MatogaUNC Project Malawi, Lilongwe, Malawi.
Ligang YangDermatology Hospital, Southern Medical University, Guangzhou, China.
Eduardo Lopez-MedinaCentro Internacional de Entrenamiento e Investigaciones Medicas - CIDEIM, Cali, Colombia.
Jonny A Garcia-LunaCentro Internacional de Entrenamiento e Investigaciones Medicas - CIDEIM, Cali, Colombia.
Irving F HoffmanDivision of Infectious Diseases, Department of Internal Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Bin YangDermatology Hospital, Southern Medical University, Guangzhou, China.
Juan C SalazarCentro Internacional de Entrenamiento e Investigaciones Medicas - CIDEIM, Cali, Colombia.
Justin D RadolfUConn Health, Farmington, Connecticut, USA.
Jonathan B ParrDivision of Infectious Diseases, Department of Internal Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Arlene C SeñaDivision of Infectious Diseases, Department of Internal Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.

Funding

Prevalence of syphilis and other sexually transmitted infections in men and transgender women who have sex with men in Cali, ColombiaU19AI144177 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RADOLF, JUSTIN D · 2019 to 2023
$11.2M
Training in Sexually Transmitted Infections and HIVT32AI007001 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SENA-SOBERANO, ARLENE C. · 1985 to 2025
$10.9M
Gates Foundation INV-036560NIAID NIH HHS T32 AI007001NIAID NIH HHS U19 AI144177
6 · The paper itself

Abstract

Among patients with primary syphilis, sensitivity of TRUST was 55% (6/11) compared to darkfield microscopy (DFM) and 60% (9/15) compared to

Indexed as

diagnosticsnon-treponemal testingSyphilis

Identifiers

PMID41282729
PMCPMC12637747

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.