Evidence map›Paper›PMID 41282696›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Ambient air pollution and the sex ratio at birth: a systematic review and narrative synthesis.

Ursula Gazeley, Hallie Eilerts-Spinelli, Jasmin Abdel Ghany, Ana Bonell, Joshua Wilde

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ursula GazeleyLeverhulme Centre for Demographic Science, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-3309-7411
Hallie Eilerts-SpinelliInternational Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States.ORCID 0000-0001-8984-0548
Jasmin Abdel GhanyLeverhulme Centre for Demographic Science, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.ORCID 0009-0001-3264-5802
Ana BonellMedical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.ORCID 0000-0001-5981-762X
Joshua WildeLeverhulme Centre for Demographic Science, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-3389-2028

Funding

Improving Age- and Cause-Specific Under-Five Mortality Rates (ACSU5MR) by Systematically Accounting Measurement Errors to Inform Child Survival Decision Making in Low Income CountriesR01HD107015 · NICHD · JOHNS HOPKINS UNIVERSITY · PI Li Liu, Tyler McCormick · 2023 to 2026
$2.1M
Gates Foundation INV-038624NICHD NIH HHS R01 HD107015Wellcome Trust
6 · The paper itself

Abstract

Ambient air pollution is associated with adverse pregnancy outcomes such as stillbirth, miscarriage, and preterm birth. However, its effects on the viability, implantation, and survival of conceptuses-largely unobserved before the clinical detection of pregnancy-remain poorly understood. Shifts in the sex ratio at birth (SRB) provide a sensitive, population-level indicator of sex-biased conception and pregnancy loss. This systematic review examined whether maternal exposure to ambient air pollution before conception and during pregnancy is associated with deviations in the SRB. We searched MEDLINE, Embase, and Global Health from inception to 12 February 2025 for observational studies assessing both ambient air pollution exposure and SRB. Eleven studies met the inclusion criteria, representing data from eight countries spanning 1970-2023. PM

Indexed as

Air pollutionconceptionin utero exposuremiscarriagepregnancy losssex ratio at birthstillbirth

Identifiers

PMID41282696
PMCPMC12633571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.