Mild hyperbaric oxygen does not attenuate mitochondrial decrease induced by detraining in mice.

Ai Takemura, Tatsuro Egawa, Kazuki Uemichi, Ryota Iyama, Haiyu Zhao, Mayuko Oba, Tatsuya Hayashi, Satoshi Fujita

Abstract read

In one paragraph

Article in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ai TakemuraRitsumeikan Global Innovation Research Organization, Ritsumeikan University, Shiga, Japan.

Tatsuro EgawaGraduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan.

Kazuki UemichiRitsumeikan Global Innovation Research Organization, Ritsumeikan University, Shiga, Japan.

Ryota IyamaGraduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan.

Haiyu ZhaoGraduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan.

Mayuko ObaGraduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan.

Tatsuya HayashiGraduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan.

Satoshi FujitaFaculty of Sport and Health Science, Ritsumeikan University, Shiga, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild hyperbaric oxygen (MHO) attenuates the muscle atrophy caused by muscle disuse. Training cessation results in the partial or complete loss of training-induced adaptations, including mitochondrial enzyme activities. The present study aimed to determine whether exposure to MHO after running training attenuated negative adaptation induced by detraining. We allocated eight-week-old mice into training (Tr), detraining after the training period (DeTr), and detraining + mild hyperbaric oxygen (DeTr + MHO, 1.3 atm absolute with 38 % oxygen) groups. Mice underwent voluntary wheel running for four weeks, followed by a two-week detraining period under normal or MHO conditions. The soleus muscle weight (mg/g BW) decreased by approximately 30 % in the DeTr and DeTr + MHO groups compared to the Tr group (

Indexed as

DetrainingMild hyperbaric oxygenMitochondriaVoluntary wheel running

Identifiers

PMID41282542

DOI10.1016/j.bbrep.2025.102341

PMCPMC12639397

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.