Evidence map›Paper›PMID 41282535›Full record

ArticleRegenerative biomaterials2025

Integrating graph convolutional networks with large language models for structured biomedical material knowledge representation.

Mufei Li, Yan Zhuang, Yao Hou, Ke Chen, Lin Han, Kefeng Wang, Xiangfeng Li, Xiangdong Zhu, Mingli Yang, Guangfu Yin and 2 more

Abstract read
In one paragraph

Article in Regenerative biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mufei LiCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Yan ZhuangCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Yao HouCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Ke ChenCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Lin HanCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Kefeng WangCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Xiangfeng LiCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Xiangdong ZhuCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Mingli YangCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Guangfu YinCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Jiangli LinCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.
Xingdong ZhangCollege of Biomedical Engineering/National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610065, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Automated literature mining is key to building structured biomedical materials databases, yet current methods struggle with large publication volumes, complex entity relations and domain-specific terminology. We propose a hierarchical natural language processing (NLP) framework for extracting structured data from biomedical materials texts. Our pipeline uses named entity recognition (NER) to identify entities such as compositions, synthesis methods and properties. Sentence-level relation extraction captures direct associations (e.g. temperature, morphology), while a paragraph-level graph convolutional network (GCN) module resolves cross-sentence co-references. Rule-based templates enhance precision in specific cases. Extracted relations are integrated into a biomedical materials knowledge graph, enabling scalable and extensible data representation. Experiments show that the sentence-level model achieves 84.7% accuracy and the GCN-based module achieves 84.0%. This approach offers an efficient pipeline for structuring complex scientific texts, reducing manual effort and supporting large-scale knowledge extraction in biomedical materials and related domains.

Indexed as

bioactive glassGraph Convolutional NetworksLarge Language Modelrelation extraction

Identifiers

PMID41282535
PMCPMC12639542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.